ID V5FWX4_BYSSN Unreviewed; 525 AA.
AC V5FWX4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN ORFNames=PVAR5_2865 {ECO:0000313|EMBL:GAD94241.1};
OS Byssochlamys spectabilis (strain No. 5 / NBRC 109023) (Paecilomyces
OS variotii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX NCBI_TaxID=1356009 {ECO:0000313|EMBL:GAD94241.1, ECO:0000313|Proteomes:UP000018001};
RN [1] {ECO:0000313|Proteomes:UP000018001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=No. 5 / NBRC 109023 {ECO:0000313|Proteomes:UP000018001};
RX PubMed=24407650; DOI=10.1128/genomeA.01162-13;
RA Oka T., Ekino K., Fukuda K., Nomura Y.;
RT "Draft genome sequence of the formaldehyde-resistant fungus Byssochlamys
RT spectabilis No. 5 (anamorph Paecilomyces variotii No. 5) (NBRC109023).";
RL Genome Announc. 2:E0116213-E0116213(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001831};
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD94241.1}.
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DR EMBL; BAUL01000081; GAD94241.1; -; Genomic_DNA.
DR AlphaFoldDB; V5FWX4; -.
DR eggNOG; KOG2828; Eukaryota.
DR HOGENOM; CLU_019748_3_0_1; -.
DR InParanoid; V5FWX4; -.
DR OrthoDB; 100792at2759; -.
DR Proteomes; UP000018001; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:GAD94241.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018001}.
FT DOMAIN 13..230
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 333..483
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 525 AA; 57713 MW; 57FA7967DBA1061F CRC64;
MAASALLKSR VQRASYLNKL AKAEDLVSLF PNGTYIGWSG FTGVGYPKKV PTALADHVEK
NNLQGQLKYN LFVGASSGAE TENRWAKLNM IERRSPHQVG KEIAKGINNG NIKFFDKHLS
MFPSDLVYGW YTKDKPGNRL DVAVIEASAI TPEGGIIPGA SVGASPELVQ MADKVIIEVN
TASPSFEGLH DITLSDLPPG RKPYLIMAPE DRIGTSYIPV DPEKVVAIVE SDYPDQTQPV
SPEDEVSQGI AGNLIEFLQH EVQHGRLPKN LLPIQSGIGN IANAVIGGLS KGGANFSNLK
VWTEVLQDSF LDLFDSGNLD FATATSIRFS PDGFKRFYDN WERYAGKLLL RSQQVSNSPE
IIRRLGCIGM NTPVEVDIYA HANSTCVMGS RMLNGLGGSA DFLRNAKYSI MHTPSVRPSK
TDPTGVSCIV PMATHVDQTE HDLDVIVTEQ GLADVRGLSP RERARVIIKK CAHPDYQPIL
TDYFDRAEFE CLKKGMGHEP HMLFQAFKMH QNLAEKGTMK INSWE
//
