ID V5G3I5_BYSSN Unreviewed; 603 AA.
AC V5G3I5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=glucan 1,3-beta-glucosidase {ECO:0000256|ARBA:ARBA00038929};
DE EC=3.2.1.58 {ECO:0000256|ARBA:ARBA00038929};
DE AltName: Full=Exo-1,3-beta-glucanase 1 {ECO:0000256|ARBA:ARBA00041265};
DE AltName: Full=Exo-1,3-beta-glucanase A {ECO:0000256|ARBA:ARBA00041261};
GN ORFNames=PVAR5_7677 {ECO:0000313|EMBL:GAD98973.1};
OS Byssochlamys spectabilis (strain No. 5 / NBRC 109023) (Paecilomyces
OS variotii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX NCBI_TaxID=1356009 {ECO:0000313|EMBL:GAD98973.1, ECO:0000313|Proteomes:UP000018001};
RN [1] {ECO:0000313|Proteomes:UP000018001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=No. 5 / NBRC 109023 {ECO:0000313|Proteomes:UP000018001};
RX PubMed=24407650; DOI=10.1128/genomeA.01162-13;
RA Oka T., Ekino K., Fukuda K., Nomura Y.;
RT "Draft genome sequence of the formaldehyde-resistant fungus Byssochlamys
RT spectabilis No. 5 (anamorph Paecilomyces variotii No. 5) (NBRC109023).";
RL Genome Announc. 2:E0116213-E0116213(2014).
CC -!- FUNCTION: Beta-glucanases participate in the metabolism of beta-glucan,
CC the main structural component of the cell wall. It could also function
CC biosynthetically as a transglycosylase.
CC {ECO:0000256|ARBA:ARBA00037254}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Successive hydrolysis of beta-D-glucose units from the non-
CC reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.;
CC EC=3.2.1.58; Evidence={ECO:0000256|ARBA:ARBA00036824};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD98973.1}.
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DR EMBL; BAUL01000271; GAD98973.1; -; Genomic_DNA.
DR AlphaFoldDB; V5G3I5; -.
DR eggNOG; ENOG502QPYU; Eukaryota.
DR HOGENOM; CLU_004624_0_1_1; -.
DR InParanoid; V5G3I5; -.
DR OrthoDB; 1431012at2759; -.
DR Proteomes; UP000018001; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31297:SF1; GLUCAN 1,3-BETA-GLUCOSIDASE I_II-RELATED; 1.
DR PANTHER; PTHR31297; GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B; 1.
DR Pfam; PF00150; Cellulase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW Hydrolase {ECO:0000256|RuleBase:RU361153};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Reference proteome {ECO:0000313|Proteomes:UP000018001}.
FT DOMAIN 268..499
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT REGION 19..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 66443 MW; 371F2E4951940A48 CRC64;
MFIGLDIHVG QPCTAREDGC GSKDAPAAAK TSLDNSPNRT VAPGRDLHPS RVYRTTRMIE
LCIPSPTLKS GCRPLAFRLT GAKCQHYPAV PDPCRPVMGG FIVLSSFTVE AAIGDRPGSG
CEICATILLF GAFPRSSFKP ASGRLIARDQ KRVYLYLVIS KCQPRYPVAA FAQICGTEIF
KIYNMLTRLP QKALLALSAL SSLAAGAPFI QERDLTFDYN NEKVRGVNLG GWLVLEPWIT
PSLFEQAGDG AIDEWSICSI LGKDEAHSRL SNHWNTWITE SDFQQIAAAG LNHVRIPIGY
WAVTPLDGEP YVQGQLNLLD QAINWARNSG IKVLIDLHGA PGSQNGFDNS GHRGSINWQQ
GDTVPQTVQA VRALAQRYAH YTDVVTAIEL INEPLIPGGI NQDALKQYYY DGWGNVRTSN
NDTTVVLHDG FLEVDSWNGF MGPGSGVWNV MMDTHHYEVF DNGQLGQDIN GHVNMACTFG
QTHLYHTDKW TVVGEWTGGI TDCAKYLNGR GLGARYDGSY PGSSWIGDCT GKYQGTVDGL
SGADKYNIRR FIEAQLDAFE MKTGWIYWTW KTEGAPEWDM QKQIAGGLFP QPLTDRQYPN
QCS
//
