ID V5I3C2_IXORI Unreviewed; 415 AA.
AC V5I3C2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Putative bone morphoproteintic protein 7 {ECO:0000313|EMBL:JAB82328.1};
DE Flags: Fragment;
OS Ixodes ricinus (Common tick) (Acarus ricinus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=34613 {ECO:0000313|EMBL:JAB82328.1};
RN [1] {ECO:0000313|EMBL:JAB82328.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland and midgut {ECO:0000313|EMBL:JAB82328.1};
RX PubMed=25765539;
RA Kotsyfakis M., Schwarz A., Erhart J., Ribeiro J.M.;
RT "Tissue- and time-dependent transcription in Ixodes ricinus salivary glands
RT and midguts when blood feeding on the vertebrate host.";
RL Sci. Rep. 5:9103-9103(2015).
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; GANP01002140; JAB82328.1; -; mRNA.
DR AlphaFoldDB; V5I3C2; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13761; TGF_beta_BMP5_like; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF298; PROTEIN 60A-RELATED; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 2: Evidence at transcript level;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 287..415
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB82328.1"
SQ SEQUENCE 415 AA; 47652 MW; 45E8F1413225BE8B CRC64;
KMSWLRLKTW TLFCITLIVI SLQICLAGYY ADNGMDQTII YRTLPKSEKR EMQQEILNLL
GFNQRPKPKL HERKYSAPRY LLDLYNSFKD EDDGEIKLDA SKAHNEFLTN NQSLRVINDS
DVIMSFLNHA HHHSPHLRHD NERRFWFDVS EVSPQERIIK AELNLYRDAQ AGSSSVGHSC
NLQINVLRHG SKIEDIILEP VDNLTIDDKS HGWLTFNVTE PLITWIAFPR ENMGLLLQIH
CDKTGHEVHP HDLGLVSAGG RSDQQPFMVA FLKSSGQAHS RVPRATRKRH SADVSYSDLD
ERPYFDTRPS GRRNSCQKRN LFVSFRDLGW QDWIIAPDGY AAFYCHGECS FPLNRNATNH
AIVQTLVHLV DPTQAPKPCC APTRLSAIMV LYFDDNSNVI LKRYKNMVVK ACGCH
//
