ID V5NLV7_HELPX Unreviewed; 564 AA.
AC V5NLV7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AHA89379.1};
GN ORFNames=U064_0447 {ECO:0000313|EMBL:AHA89379.1};
OS Helicobacter pylori BM012S.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1407463 {ECO:0000313|EMBL:AHA89379.1, ECO:0000313|Proteomes:UP000018543};
RN [1] {ECO:0000313|EMBL:AHA89379.1, ECO:0000313|Proteomes:UP000018543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BM012S {ECO:0000313|EMBL:AHA89379.1,
RC ECO:0000313|Proteomes:UP000018543};
RX DOI=10.1371/journal.pone.0082187;
RA Linz B., Windsor H.M., Gajewski J.P., Hake C.M., Drautz D.I.,
RA Schuster S.C., Marshall B.J.;
RT "Helicobacter pylori genomic microevolution during naturally occurring
RT transmission between adults.";
RL PLoS ONE 8:E82187-E82187(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP006889; AHA89379.1; -; Genomic_DNA.
DR AlphaFoldDB; V5NLV7; -.
DR KEGG; hez:U064_0447; -.
DR PATRIC; fig|1407463.3.peg.455; -.
DR HOGENOM; CLU_000445_107_21_7; -.
DR Proteomes; UP000018543; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF17200; sCache_2; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 211..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 232..287
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 285..549
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 564 AA; 62614 MW; A26F50B103EB4AD6 CRC64;
MFSSMFASLG TRIMLVVLAA LLGLGGLFIG FVKVMQKDVL AQLMEHLETG QYKKREKTLA
YMTKIIEQGI HEYYKDFDNA TARKMALDYF KRINDDKGMI YMVVVDKNGV VLFDPVNPKT
VGQSGLDAQS VDGVYYVRGY LEAAKKGGGY TYYKMPKYDG GVPEKKFAYS HYDEVSQMVI
ATTSYYTDIN TENKAIKESV NKVFNENTTK LFLWILTATI ALVVLTLIYA KLRIVKRIDE
LVLKINAFSH GDKDLRAKID VGDRNDEISQ VGRGINLFVE NARLIMEEIK GISTSNKTSM
DKLVQIAQET QKSMKNSSTT LNSVKNKATD VASMMNTSIE QSQGLRKRLI ETQGLVKESK
DAIGDLFSQI IESAHTEEEL SSKVEQLSRN ADDVKSILDI INDIADQTNL LALNAAIEAA
RAGEHGRGFA VVADEVRNLA GRTQKSLAEI NSTIMVIVQE INAVSSQMNL NSQKMERLSD
MSKSVQETYE KMSSNLSSVV SDSNQSMDDY AKSGHQIEVM VSDFAEVEKV ASKTLADSSD
ILNIATHVSG TTMSLDKQVN LFKT
//
