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Database: UniProt
Entry: V5RUK6_9BACT
LinkDB: V5RUK6_9BACT
Original site: V5RUK6_9BACT 
ID   V5RUK6_9BACT            Unreviewed;       451 AA.
AC   V5RUK6;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   05-JUL-2017, entry version 28.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=RAAC3_TM7C00001G0314 {ECO:0000313|EMBL:AHB42176.1};
OS   Candidatus Saccharibacteria bacterium RAAC3_TM7_1.
OC   Bacteria; Candidatus Saccharibacteria.
OX   NCBI_TaxID=1394711 {ECO:0000313|EMBL:AHB42176.1, ECO:0000313|Proteomes:UP000018523};
RN   [1] {ECO:0000313|EMBL:AHB42176.1, ECO:0000313|Proteomes:UP000018523}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RAAC3_TM7_1 {ECO:0000313|EMBL:AHB42176.1,
RC   ECO:0000313|Proteomes:UP000018523};
RA   Kantor R.S., Wrighton K.C., Handley K.M., Sharon I., Hug L.A.,
RA   Castelle C.J., Thomas B.C., Banfield J.F.;
RT   "Small genomes and sparse metabolisms of sediment-associated bacteria
RT   from four candidate phyla.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP006915; AHB42176.1; -; Genomic_DNA.
DR   EnsemblBacteria; AHB42176; AHB42176; RAAC3_TM7C00001G0314.
DR   KEGG; sbe:RAAC3_TM7C01G0314; -.
DR   PATRIC; fig|1394711.4.peg.275; -.
DR   KO; K02313; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000018523; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018523};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018523}.
FT   DOMAIN      149    279       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      359    428       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     157    164       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   451 AA;  50907 MW;  A2E4A1C91D5AD823 CRC64;
     MSHSLWQSVL GEIELSVSHA TYMTWFKNTE LVNQSASEVT IAVPNIFAKR QFEVKFDEQI
     RGVLAKNGVS PKTVNYTVKT TVQRPTASRE TTISHAADRL VAPRQVEHSA LTPKTTLNPR
     YSFESFIVGS SNDLAYSACQ AVAKNPGTKY NPLFLYGGVG LGKTHLIQAV GNEIIKHQPE
     KVVLYISSET FVNDFLESIR YKKKGFADKY RNVDVLIVDD MQFIAGKEKT QEEFFHTFNA
     LHQANKQIII SSDKPPRNIP TLTERLRSRF EWGMSIDIQM PDFETRCAIL EAKSALSGVE
     VARETIEYLA NNIKTNVREL EGALNQLLAY AEMRGVPADI STAEGLIGNV RHSRPQHLNA
     RQIIDKTARH FSLSAQEICS PKRDKHIVTP RQIAMYLLRS ELHLSFPKIA TELGRKDHTT
     AIHSVEKIEK AVKLDFLIRE QVADIRDKLY A
//
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