ID   V5TLJ1_HALHI            Unreviewed;       831 AA.
AC   V5TLJ1;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Dimethylsulfoxide reductase {ECO:0000313|EMBL:AHB66176.1};
GN   ORFNames=HISP_09230 {ECO:0000313|EMBL:AHB66176.1};
OS   Haloarcula hispanica N601.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=1417673 {ECO:0000313|Proteomes:UP000018572};
RN   [1] {ECO:0000313|EMBL:AHB66176.1, ECO:0000313|Proteomes:UP000018572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N601 {ECO:0000313|EMBL:AHB66176.1,
RC   ECO:0000313|Proteomes:UP000018572};
RX   PubMed=24625874;
RA   Ding J.Y., Chiang P.W., Hong M.J., Dyall-Smith M., Tang S.L.;
RT   "Complete Genome Sequence of the Extremely Halophilic Archaeon Haloarcula
RT   hispanica Strain N601.";
RL   Genome Announc. 2:e00178-14(2014).
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; CP006884; AHB66176.1; -; Genomic_DNA.
DR   RefSeq; WP_014040610.1; NC_023013.1.
DR   AlphaFoldDB; V5TLJ1; -.
DR   GeneID; 23804818; -.
DR   KEGG; hhn:HISP_09230; -.
DR   HOGENOM; CLU_000422_13_3_2; -.
DR   Proteomes; UP000018572; Chromosome 1.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 2.
DR   Gene3D; 2.20.25.90; ADC-like domains; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR43742:SF6; OXIDOREDUCTASE YYAE-RELATED; 1.
DR   PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          56..113
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
FT   REGION          803..831
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        803..818
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   831 AA;  92437 MW;  D158029921F1921E CRC64;
     MTDDDGVYRR DVLKASGAAA ALGLGGGEFF QTLVESGDGT GPSNRDSGIE SYVGQNEVIQ
     TVCSPNCRGK CPIDVHVRDG QVKKVEPHPP EDEQYKRACV LGLSHTQRVY DPTRLKYPMK
     RTDWSPDEPN PDGRGPDAEF ERVSWDEALD LVADKMQSLK ADFGPESVLF HVGFGNYGQS
     GTAFSRLASL FGSTQPASTI DTNVGRGFNR VTGTGFYLPS TNEAEDWENA NTIIVWGSDL
     FSSQFQMDAS EVLDAVENGA KLVVVDPVYT TTASKADLWL PVKPGKDVHL ALAMMHTVFE
     DGTYDEQFLR QRTTGPALVR KDTGDLLKSS TVFDDGSDDQ VVAVEQGSNT AVELEPETDG
     PYALFGEFTV DGIECETALT RLRDHVADYA PSEVAEQTGV DAENIRTAVR WLATRGPGGI
     APSYALGRYK HGHIFGQTYA MLMGLTGDYG RHGNIHAHHS GGATLSTGGW STPEDADPGP
     SVRFSDYPDA MIDGDPHKVR AVYSIESNMM GNQFPDRQRF REAIKSLEMF VVADMHHTDT
     VQHADIIFPV PHWFEQEDIV SSWGSHPHIS YRHKVQEPMW EARDDYYAIR GLAERLGFGD
     YFPETKRELL RELASRDDAI DFETLSEQGT QKKQNIPIVK FTDAFPTDTG RIKMYDDDAP
     SEEGVTFDLP RPLEDRTADD YEKADEYPLM FMQKHSRFRI HSQYEMLNWV REVNPEPQLD
     IHPSDAKARG IEDGEYVRVH NDRGEMIVKA KYNEAFQPGL VNTDQGWWSR DYVAGHHNDL
     THNEVSEVGQ TMAFYDVRVE VEPAPDDVDT DKYEADNPRG AGADAPRAGG D
//