ID V5TQG7_HALHI Unreviewed; 458 AA.
AC V5TQG7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Phosphomethylpyrimidine kinase {ECO:0000313|EMBL:AHB67182.1};
GN ORFNames=HISP_14650 {ECO:0000313|EMBL:AHB67182.1};
OS Haloarcula hispanica N601.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=1417673 {ECO:0000313|Proteomes:UP000018572};
RN [1] {ECO:0000313|EMBL:AHB67182.1, ECO:0000313|Proteomes:UP000018572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N601 {ECO:0000313|EMBL:AHB67182.1,
RC ECO:0000313|Proteomes:UP000018572};
RX PubMed=24625874;
RA Ding J.Y., Chiang P.W., Hong M.J., Dyall-Smith M., Tang S.L.;
RT "Complete Genome Sequence of the Extremely Halophilic Archaeon Haloarcula
RT hispanica Strain N601.";
RL Genome Announc. 2:e00178-14(2014).
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DR EMBL; CP006884; AHB67182.1; -; Genomic_DNA.
DR AlphaFoldDB; V5TQG7; -.
DR KEGG; hhn:HISP_14650; -.
DR HOGENOM; CLU_035788_0_0_2; -.
DR Proteomes; UP000018572; Chromosome 1.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR019293; ThiN.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF10120; ThiP_synth; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AHB67182.1};
KW Transferase {ECO:0000313|EMBL:AHB67182.1}.
FT DOMAIN 29..270
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
SQ SEQUENCE 458 AA; 46816 MW; 4313AA86637E771A CRC64;
MWPPVKSSGM TRADAPVTPP VVLTVAGSDS GGGAGIQADV KTIEACGGFG TSAITSITAQ
NTTGVQGQHL LPIEQIEAQI EAVTGDFDVA AVKTGMLATS DVIDLVVEHA ADLPNLVVDP
VMVAASGDRL LAAEAEDAYE TLIAEATLVT PNADEAAVLT GRDVDDPEAA EQAGRDLVEM
GADSALVKGG HVPGDAVVDT LVTEDGVTTF RHDRIDTEAT HGSGCTLSSA IATQLAHGDD
LPTAVGDSID LLASAVRYNL DVGEGPGAVH HLVQTRNDAA RHPTGEAVER AVSALVKADV
STLVPERGMT VAGATPYAET PDAVAAVEGR IARTMDGVRP NRGVRFGAST TVARALLAAR
EHDPAVRFAV DCRLTDAIED ALASLDGSVA TYDPDEQPDE VSDDAAAQWG IDRAFGTSDG
TPVAVVGREG VGTDGRVMLL AADVDDLVSR VETIGDGA
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