ID   V5TTZ7_HALHI            Unreviewed;       882 AA.
AC   V5TTZ7;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Glycine cleavage system protein T {ECO:0000313|EMBL:AHB68170.1};
GN   ORFNames=HISP_19085 {ECO:0000313|EMBL:AHB68170.1};
OS   Haloarcula hispanica N601.
OG   Plasmid pHH406 {ECO:0000313|EMBL:AHB68170.1,
OG   ECO:0000313|Proteomes:UP000018572}.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=1417673 {ECO:0000313|Proteomes:UP000018572};
RN   [1] {ECO:0000313|EMBL:AHB68170.1, ECO:0000313|Proteomes:UP000018572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N601 {ECO:0000313|EMBL:AHB68170.1,
RC   ECO:0000313|Proteomes:UP000018572};
RC   PLASMID=Plasmid pHH406 {ECO:0000313|Proteomes:UP000018572};
RX   PubMed=24625874;
RA   Ding J.Y., Chiang P.W., Hong M.J., Dyall-Smith M., Tang S.L.;
RT   "Complete Genome Sequence of the Extremely Halophilic Archaeon Haloarcula
RT   hispanica Strain N601.";
RL   Genome Announc. 2:e00178-14(2014).
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; CP006887; AHB68170.1; -; Genomic_DNA.
DR   AlphaFoldDB; V5TTZ7; -.
DR   KEGG; hhn:HISP_19085; -.
DR   HOGENOM; CLU_007884_11_2_2; -.
DR   Proteomes; UP000018572; Plasmid pHH406.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Plasmid {ECO:0000313|EMBL:AHB68170.1}.
FT   DOMAIN          51..412
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          416..470
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          473..754
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          802..864
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
FT   REGION          17..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..31
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   882 AA;  97769 MW;  2C748A5068AC7DB2 CRC64;
     MVLASFRKGA TLKTDDVESY HHERREYSSV RQHTGETAMS SNSLPSAAKT VLIGGGIVGN
     SLAYHLARMG REDISILDKG PFPDPGGSTG HASNFLMPVE HSKEMTHLTR RSIEQYKDMD
     TFTNSGGIEV ARTEARVEEL KRRIQSAKAW GEPAELLTPE EVEALVPYVN TDLVKAGFYS
     TGAGTCDPLR AGEVMRARAD EYTDGGLHVS PNTEVLDLHV EDGSIAAVET DRGTVTADEV
     VIAAGLWSPK LAEMAGVEIP LTPAVHQMVS VGPISFFEDY EGEISFPVVR DMDTQMYERQ
     HGNDLEVGSY QHRPILWDVE DIPSIDEAPL SPTQPPLTDD AFEQSMADAL EIVPELLDDP
     EAGIRHEIDG LLSQTPDGAP LLGPLQDVDG LWSCAAIWIK EAPAIGEAVA QWMTRGWSDI
     DLHGADVNRF YEYGNSRSFV KDRASEGFQK IYDIVHPAEQ YQSARELRTS PFYEKQADLD
     AEFFEAAGWE RPQWYESNSD LLDRYEDELA EFRRPNEWDS RWWSPNILAE HLHTREHVSM
     IGDMGFSIFD FRGSDVVDYL ERMAVGRIDV DVGKTVYTPI LAENGGFVSD LTIARLGPKH
     YRVVTGGAAG GSDRSWFGGH IPDDADVTMI DRSESLCTLG VWGPNARDMV EGVTEEDMSH
     DAFEPYTAQE ITVGEVDAWA MRLSYIGEQG WEIYAPMGQG RRLWDVLWEA GQDHNVRPAG
     MGVYGTTGRL EKGYRLFGHE LELEYNPAEA GLTFHGVKDA DFIGKEAYAE AIDEENTATL
     CTLSVDDHAP EGGERRFMLG NEPVLDENGD VLVDDEGRRS YVTSAGTGPS VGKHLLMAYL
     PQSHAEEGRS LQVEYMGQQY PVTVEVVGSR PLFDPENERI RS
//