ID V5WET8_9SPIO Unreviewed; 400 AA.
AC V5WET8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000313|EMBL:AHC14322.1};
DE EC=2.3.1.51 {ECO:0000313|EMBL:AHC14322.1};
GN ORFNames=L21SP2_0902 {ECO:0000313|EMBL:AHC14322.1};
OS Salinispira pacifica.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Spirochaetaceae;
OC Salinispira.
OX NCBI_TaxID=1307761 {ECO:0000313|EMBL:AHC14322.1, ECO:0000313|Proteomes:UP000018680};
RN [1] {ECO:0000313|EMBL:AHC14322.1, ECO:0000313|Proteomes:UP000018680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L21-RPul-D2 {ECO:0000313|EMBL:AHC14322.1,
RC ECO:0000313|Proteomes:UP000018680};
RX PubMed=26203324; DOI=10.1186/1944-3277-10-7;
RA Ben Hania W., Joseph M., Schumann P., Bunk B., Fiebig A., Sproer C.,
RA Klenk H.P., Fardeau M.L., Spring S.;
RT "Complete genome sequence and description of Salinispira pacifica gen.
RT nov., sp. nov., a novel spirochaete isolated form a hypersaline microbial
RT mat.";
RL Stand. Genomic Sci. 10:7-7(2015).
CC -!- FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid
CC by incorporating acyl moiety at the 2 position.
CC {ECO:0000256|ARBA:ARBA00037183}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-
CC sn-glycero-3-phosphate + CoA; Xref=Rhea:RHEA:19709,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342,
CC ChEBI:CHEBI:58608; EC=2.3.1.51;
CC Evidence={ECO:0000256|ARBA:ARBA00001141};
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DR EMBL; CP006939; AHC14322.1; -; Genomic_DNA.
DR RefSeq; WP_024267253.1; NC_023035.1.
DR AlphaFoldDB; V5WET8; -.
DR STRING; 1307761.L21SP2_0902; -.
DR KEGG; slr:L21SP2_0902; -.
DR eggNOG; COG0204; Bacteria.
DR HOGENOM; CLU_055816_0_0_12; -.
DR OrthoDB; 9803035at2; -.
DR Proteomes; UP000018680; Chromosome.
DR GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd07989; LPLAT_AGPAT-like; 1.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10434; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR10434:SF60; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE LPAT1, CHLOROPLASTIC; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:AHC14322.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018680};
KW Transferase {ECO:0000313|EMBL:AHC14322.1}.
FT DOMAIN 47..159
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 400 AA; 45591 MW; FB433F613277D8D6 CRC64;
MQKTCRRFLI QKLSYILIRP FAWLFFITRY RVKFEIPPEI RDLKGSYVLL GNHVNKWDPF
IATIGLKRLV NFIASDFVFR KPFLAWLLGL LGAVPKVKFR SDMGSLRTLM DVRSCGGIIG
IFPEGHTNWS GKTMEITPST GKLLRLLRAP VVAVNIQGGY ISEPRWHRGI LAPGIVMKFS
LLFTENEVRS LSIAQLNARL QIALEHNEWD YLREHPRELP AVDRARGIEH AVFICPDCGS
IGSLRSRNNS LRCTVCSGEL EINRYGFPSE ATFQNSFPDI ALWDQWQQDR LISLISGQTG
QAIFEDGPAR FAYAPDGKTF SRFSRWGTLK FSGTSLVLHG EESIEYEIRT LSGIGVQNSE
QLEFYVNNTL TTIEFKEDFV SPYKWLSALN HAQVFLGEEE
//
