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Database: UniProt
Entry: V6EYT0_9PROT
LinkDB: V6EYT0_9PROT
Original site: V6EYT0_9PROT 
ID   V6EYT0_9PROT            Unreviewed;       460 AA.
AC   V6EYT0;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   25-OCT-2017, entry version 34.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:CDK97216.1};
GN   ORFNames=MGMSRv2__0001 {ECO:0000313|EMBL:CDK97216.1};
OS   Magnetospirillum gryphiswaldense MSR-1 v2.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Magnetospirillum.
OX   NCBI_TaxID=1430440 {ECO:0000313|EMBL:CDK97216.1, ECO:0000313|Proteomes:UP000018922};
RN   [1] {ECO:0000313|EMBL:CDK97216.1, ECO:0000313|Proteomes:UP000018922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSR-1 {ECO:0000313|EMBL:CDK97216.1};
RX   PubMed=24625872; DOI=10.1128/genomeA.00171-14;
RA   Wang X., Wang Q., Zhang W., Wang Y., Li L., Wen T., Zhang T.,
RA   Zhang Y., Xu J., Hu J., Li S., Liu L., Liu J., Jiang W., Tian J.,
RA   Li Y., Schuler D., Wang L., Li J.;
RT   "Complete Genome Sequence of Magnetospirillum gryphiswaldense MSR-1.";
RL   Genome Announc. 2:e00171-e00114(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; HG794546; CDK97216.1; -; Genomic_DNA.
DR   RefSeq; WP_024078262.1; NC_023065.1.
DR   EnsemblBacteria; CDK97216; CDK97216; MGMSRv2__0001.
DR   KEGG; mgy:MGMSRv2__0001; -.
DR   KO; K02313; -.
DR   Proteomes; UP000018922; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018922};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018922}.
FT   DOMAIN      157    287       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      368    437       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     165    172       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   460 AA;  51512 MW;  2B8A06A9A0881E56 CRC64;
     MINAEWDRIK VRLRDEVGDA AYRSWLRPIT LHQAADGMVR LGLPTRFMRD WVATHYGERI
     RALWGAENPA LHAIEIVVAN RTGLEPAPAA AAAAAKAVAS NVTPLRPRPA APCAPADVDE
     LGAQLDPRFT FKNFVVGKPN EFAHAAAIRV AEASAVSFNP LFLYGGVGLG KTHLMHAIAH
     HIREHNPARR VLYLSAEKFM YRFIRALRSQ DTMSFKEQFR SVDVLMVDDV QFIAGKDATQ
     EEFFHTFNAL VDQGRQIVIS ADKSPSDLEG MEDRLRSRLN SGLVADLHAT TYELRLGILQ
     SKAEQMGAVV PQKVMEFLAH KITSNVRELE GALNRVIAHS QLVGRSITLE STQDVLHDLL
     KASDRRITIE EIQKRVAEHF NIKLAEMSSA RRSRQVARPR QVAMYLAKQL TSRSLPEIGR
     KFGGRDHTTV MHAVKKIEEL RSSDQGFSED VELLRRMLQG
//
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