ID V6JSH2_STRNV Unreviewed; 303 AA.
AC V6JSH2;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Epimerase {ECO:0000313|EMBL:EST22076.1};
GN ORFNames=M877_30960 {ECO:0000313|EMBL:EST22076.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST22076.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST22076.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST22076.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. SDR39U1 subfamily. {ECO:0000256|ARBA:ARBA00009353}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST22076.1}.
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DR EMBL; AWQW01000222; EST22076.1; -; Genomic_DNA.
DR RefSeq; WP_023542269.1; NZ_CM002280.1.
DR AlphaFoldDB; V6JSH2; -.
DR STRING; 193462.BBN63_25675; -.
DR PATRIC; fig|1352941.4.peg.6289; -.
DR eggNOG; COG1090; Bacteria.
DR HOGENOM; CLU_047373_0_2_11; -.
DR OrthoDB; 9801773at2; -.
DR Proteomes; UP000017971; Chromosome.
DR CDD; cd05242; SDR_a8; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013549; DUF1731.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR010099; SDR39U1.
DR NCBIfam; TIGR01777; yfcH; 1.
DR PANTHER; PTHR11092:SF0; EPIMERASE FAMILY PROTEIN SDR39U1; 1.
DR PANTHER; PTHR11092; SUGAR NUCLEOTIDE EPIMERASE RELATED; 1.
DR Pfam; PF08338; DUF1731; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
FT DOMAIN 6..215
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT DOMAIN 251..292
FT /note="DUF1731"
FT /evidence="ECO:0000259|Pfam:PF08338"
SQ SEQUENCE 303 AA; 32265 MW; 0D0D42EE528E02BC CRC64;
MGSMRIAITG SNGLIGTALT RSLRADGHDV VRLVRHPSRA GDEVEWDPAR QYVDVSGLYG
CEAVVHLAGA GVADHRWTDA YKKEIRDSRV LGTAAIAEAV ASLDTPPRVL VCGSAIGFYG
DTGDRAVDES APPGEGFLPS VCVEWEDAAA PATDAGVRTV FARTGLVVAR EGGAWGRLFP
IFRAGLGGRI GDGRQYWSFI SLHDHVAALR HLIDTESLSG PVNLTAPEPV TNREVTAAMG
RVLHRPTVFA VPSAALRVAL GEFSVDVLSS QRVRPRRLLE SGFTFAFPKI DESIVSAMAP
ATR
//
