ID V6JUI2_STRRC Unreviewed; 424 AA.
AC V6JUI2;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:EST23570.1};
GN ORFNames=M878_33005 {ECO:0000313|EMBL:EST23570.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST23570.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST23570.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST23570.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST23570.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWQX01000281; EST23570.1; -; Genomic_DNA.
DR RefSeq; WP_023551294.1; NZ_CM002285.1.
DR AlphaFoldDB; V6JUI2; -.
DR STRING; 1352936.M878_33005; -.
DR PATRIC; fig|1352936.5.peg.6876; -.
DR HOGENOM; CLU_000445_20_2_11; -.
DR OrthoDB; 5242012at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR025828; Put_sensor_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF13796; Sensor; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EST23570.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 17..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 333..423
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
SQ SEQUENCE 424 AA; 45169 MW; E1679F8736C8E838 CRC64;
MNTDTKSHDV RSRARRVLLA GVQGLVLALV VLPCGVAFLV LTLVSLALIP LGIGLVTTPA
ILTGVRALAD ARRRLAAEWC GIRIPAVYRP HHEGAKPWTR TFTLLRDPQV RRDLRWLPVD
FTAGFVTALL PAVLVFCPIE GFLLAAGLWR AFVPATGDAY WYLFVPVSGQ GTAFLAALLG
AVLLVVASRL APRTVKAHFE LTRAVLGGDA ELAERVRVLT ETRRDAVDTS AAELRRIERD
LHDGAQARLV AMGMDLGTIE SLVEHDPAQA KRLLAQARRN SAEALEELRD LVRGIHPPVL
AERGLGDAVR ALALRLPLPA EVSVELPGRA DAPVESAAYF AVSEVLTNAV KHSGADRIWA
DVHHSDGRLR ITVTDNGKGG AAIGAGSGLA GVERRLGTFD GVLAVSSPAG GPTLVTMEIP
CALS
//
