ID   V6K408_STRNV            Unreviewed;       467 AA.
AC   V6K408;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Ricin B lectin domain-containing protein {ECO:0000259|Pfam:PF14200};
GN   ORFNames=M877_18400 {ECO:0000313|EMBL:EST26783.1};
OS   Streptomyces niveus NCIMB 11891.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST26783.1, ECO:0000313|Proteomes:UP000017971};
RN   [1] {ECO:0000313|EMBL:EST26783.1, ECO:0000313|Proteomes:UP000017971}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST26783.1,
RC   ECO:0000313|Proteomes:UP000017971};
RX   PubMed=24407644;
RA   Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT   "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT   Aminocoumarin Antibiotic Novobiocin.";
RL   Genome Announc. 2:e01146-e01113(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EST26783.1}.
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DR   EMBL; AWQW01000129; EST26783.1; -; Genomic_DNA.
DR   AlphaFoldDB; V6K408; -.
DR   PATRIC; fig|1352941.4.peg.3756; -.
DR   eggNOG; COG2730; Bacteria.
DR   eggNOG; COG3386; Bacteria.
DR   HOGENOM; CLU_536269_0_0_11; -.
DR   Proteomes; UP000017971; Chromosome.
DR   CDD; cd14953; NHL_like_1; 1.
DR   CDD; cd00161; RICIN; 1.
DR   Gene3D; 2.80.10.50; -; 1.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR001258; NHL_repeat.
DR   InterPro; IPR035992; Ricin_B-like_lectins.
DR   InterPro; IPR000772; Ricin_B_lectin.
DR   PANTHER; PTHR13833; -; 1.
DR   PANTHER; PTHR13833:SF71; NHL DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01436; NHL; 3.
DR   Pfam; PF14200; RicinB_lectin_2; 1.
DR   SUPFAM; SSF101898; NHL repeat; 1.
DR   SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR   PROSITE; PS51125; NHL; 3.
DR   PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          56..86
FT                   /note="NHL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT   REPEAT          106..142
FT                   /note="NHL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT   REPEAT          223..254
FT                   /note="NHL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT   DOMAIN          356..442
FT                   /note="Ricin B lectin"
FT                   /evidence="ECO:0000259|Pfam:PF14200"
SQ   SEQUENCE   467 AA;  48747 MW;  18F28C7AE4C7E2B9 CRC64;
     MNRPYGIAVD SIGTVYFSDY VNNRLRKITT DGKISTVAGA AVGYRGDDGP AASALLNAPR
     EIAVDSAGTV YITDSANNRV RKITTDGTIS TVAGTGTAGF GGDGGPATKA QLNYPLGVAV
     DSTGALYITD HRNSRIRKVT ADGNISTVAG SGVAGFKGDG EPAVSAHLKT PYALAVDGMD
     ELYIADAGNN RVRKVASDGT ISTVAGSGVA GFRGDDGLAT SAQLNFPLGV VVDSTGTLYI
     SDYNNNRVRK VAADGTISTV AGTGTAGYGG DDGPAASAQL NKPFGLAVDC VDTLYIADHL
     NNRVRKIASE KMAGLPESGA VVSWANVRSR LRMGVLREST RDGAEIHQSL TSPRAHQQWR
     LIAAGQDDGD VLYRIENVRS GKVLEVVGGG TADGAVVAQR AYEGSGADHQ QWRLIPVGSV
     TDTPRVYEIA NRNSGLLLRV DTNAPVVIKQ YGAQGDHRDR QWQLLPV
//