ID V6K562_STRRC Unreviewed; 250 AA.
AC V6K562;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:EST24104.1};
GN ORFNames=M878_31725 {ECO:0000313|EMBL:EST24104.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST24104.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST24104.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST24104.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST24104.1}.
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DR EMBL; AWQX01000270; EST24104.1; -; Genomic_DNA.
DR AlphaFoldDB; V6K562; -.
DR STRING; 1352936.M878_31725; -.
DR PATRIC; fig|1352936.5.peg.6610; -.
DR HOGENOM; CLU_062618_6_0_11; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF2; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017984};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..61
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 62..246
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 250 AA; 26927 MW; 428E0592B95D0A95 CRC64;
MTRALDILEL FLDGDGTLSA PDIVRKLQLP RTTVHELVTT LAARSYIVPV PGQPGRYRLG
VRPYQLGSRY AEQLDLAAEG QQVARSVAET CDETVHVAIL EGTDVIYIAK VDSTHAVRMV
SAAGRRLPAH CTSVGKMLLA SLPEQELAAR IPDGAELTAM TPNSITDPAV LREALAEIRR
HGIAVESRES NPDVSCVAAP VRDRTGQVVA ALSVSVPMIR WSDERRAELE QLAAKGAAEL
SERLGHRGTA
//
