ID V6K852_STRNV Unreviewed; 304 AA.
AC V6K852;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:EST28213.1};
GN ORFNames=M877_15100 {ECO:0000313|EMBL:EST28213.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST28213.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST28213.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST28213.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST28213.1}.
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DR EMBL; AWQW01000109; EST28213.1; -; Genomic_DNA.
DR RefSeq; WP_023539268.1; NZ_CM002280.1.
DR AlphaFoldDB; V6K852; -.
DR STRING; 193462.BBN63_12585; -.
DR PATRIC; fig|1352941.4.peg.3087; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_11; -.
DR OrthoDB; 3673085at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08423; PBP2_LTTR_like_6; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 304 AA; 31902 MW; 248583FD9C3606B9 CRC64;
MIEARHLRVL RAVAATGSFS AAARELGCTQ PAVSQQMKVL EASVGTTLLI RTSREMRLTQ
AGEVLVRHAT GILSGLTAAE EEVAAIAGLR AGRVRLVSFP SGSSTLVPAA LAALRAAHPG
TRVSLVDAEP PRSVEMLRDG DCDVALAFRY DSVHDDSAGG AAEEWGDLVV RPLLSDRLVG
LLPEGHRLAG ADTVSIADLA DESWIAGCPR CRHQLVDACE KAGFTPRIDF ATDDYPAVIG
LVGAGLGVAF LPELAMESVL PKAARTVTVE PAVRREIVAL TLPDLARVPA VAATLDQLER
AAAR
//
