ID V6K9J0_STRNV Unreviewed; 380 AA.
AC V6K9J0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN ORFNames=M877_13890 {ECO:0000313|EMBL:EST28830.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST28830.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST28830.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST28830.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST28830.1}.
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DR EMBL; AWQW01000099; EST28830.1; -; Genomic_DNA.
DR RefSeq; WP_023539032.1; NZ_CM002280.1.
DR AlphaFoldDB; V6K9J0; -.
DR PATRIC; fig|1352941.4.peg.2844; -.
DR eggNOG; COG2518; Bacteria.
DR HOGENOM; CLU_037629_0_1_11; -.
DR OrthoDB; 5143400at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR026448; Methyltr_grasp.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR04188; methyltr_grsp; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:EST28830.1};
KW Transferase {ECO:0000313|EMBL:EST28830.1}.
FT REGION 82..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 380 AA; 40820 MW; FBB98FC3CF920B5D CRC64;
MSSTATELRA ALVDRLTEDG TLTEPEWSAA ARAVSRELFT GSYFLPVAGS FPTAYRPVRE
GEPGWLEGVY TDETLITQLD GRTRPDDVAE GAVPGSPSSS STLPSLVLRM WHQLGAEAGH
RVLEIGTGTG YSTALGAHRL GDANLTSVEY DPTVGRAAAT VLNAAGFSPR LIIGDGLRGD
PDGGQYDRLI ATCSVRYIPL PWLHQVRPGG KILVTLSGWS YANALALLDV TSPGEATGRF
LPGCTSFMIA RPHDRPPRPT LALLPGEERP SRIDPAKLDD WTGGWVAQLA APSAERMGAG
AEQILWDVST GSQARTAPDT KGWSVVQRGP VRLWDRVERA MRLWQDAGEP HQQEFGITVS
AAGQRVWLGT HDGPSWDLPI
//
