ID V6KK57_STRNV Unreviewed; 350 AA.
AC V6KK57;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Autoinducer 2 import system permease protein LsrC {ECO:0000256|ARBA:ARBA00039382};
GN ORFNames=M877_04245 {ECO:0000313|EMBL:EST32482.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST32482.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST32482.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST32482.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC autoinducer 2 (AI-2) import. Probably responsible for the translocation
CC of the substrate across the membrane. {ECO:0000256|ARBA:ARBA00025439}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC (LsrB). {ECO:0000256|ARBA:ARBA00011262}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST32482.1}.
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DR EMBL; AWQW01000035; EST32482.1; -; Genomic_DNA.
DR RefSeq; WP_023537154.1; NZ_CM002280.1.
DR AlphaFoldDB; V6KK57; -.
DR STRING; 193462.BBN63_04040; -.
DR PATRIC; fig|1352941.4.peg.874; -.
DR eggNOG; COG1172; Bacteria.
DR HOGENOM; CLU_028880_0_1_11; -.
DR OrthoDB; 3185552at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06579; TM_PBP1_transp_AraH_like; 1.
DR InterPro; IPR001851; ABC_transp_permease.
DR PANTHER; PTHR32196; ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED; 1.
DR PANTHER; PTHR32196:SF29; AUTOINDUCER 2 IMPORT SYSTEM PERMEASE PROTEIN LSRC; 1.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 35881 MW; DEEF631F3653EEBC CRC64;
MTSTLHKPTP DPTPPAPAEE GRSARSLVDA VFRAREIAIG GALALLILGT WLANPGFLDD
QGVKDLLLNS SILVLLAVGQ SVVVMTRNID LSVGSVVGLT AFACGHFVSG TDHSALTVVL
LGIALGTVCG LVSGALVSFG RVPALVVTLG MLYIIQGIDH AWAHGEQINA ANVPDGVLSL
GSGSVLGVPY LPLISAAVLA ATGYFLRTYR SGRELYAIGS SPDAARLAGI PVRRRILAAY
AFSGAIAGFA GALWLARFGT VVADAANGWE LTVVSAVVVG GVAITGGTGS VWGAALGALL
LTTIGSALVV LKVDSFWQQA ITGVLLLAAI TTDRVVQVRT TSALRKRSRR
//
