ID V6KM71_STRNV Unreviewed; 360 AA.
AC V6KM71;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Geranylgeranyl diphosphate synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=M877_02255 {ECO:0000313|EMBL:EST33172.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST33172.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST33172.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST33172.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST33172.1}.
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DR EMBL; AWQW01000021; EST33172.1; -; Genomic_DNA.
DR RefSeq; WP_023536768.1; NZ_CM002280.1.
DR AlphaFoldDB; V6KM71; -.
DR STRING; 193462.BBN63_06045; -.
DR PATRIC; fig|1352941.4.peg.463; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_2_1_11; -.
DR OrthoDB; 4497239at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 360 AA; 38254 MW; 73B1F8C146BB22CA CRC64;
MAKTCPTTSL PDLPSVRHKV STALTGFLDA KDQAAPGTEL LYLTTTLRAF LTSGKRLRSV
LCVYGWQAAG GDGELTAAIR AAASLELFQV FALVHDDVMD DSDVRRGQPS AHRALATAYT
DSGGPQGRAE AHGLGAAVLL GDLALVWSDE LLHSAVLDPS RLADVLPLVA EMRSELMYGQ
LLDLQTTGRL TGDVETALHI IRYKTAKYTV ERPLHIGAAV AGAGAPVLDA CTAFGIPLGE
AFQLRDDLLG VFGDPAETGK SILDDLREGK GTVLMALAVQ RASSAERKTL RALVGRSDLD
EDLAAEVRAI LESTDARRTV EEMITERRDA AFAALDDAPF PAAAVAQLRQ IALVATERQT
//
