ID V6KMD9_STRNV Unreviewed; 355 AA.
AC V6KMD9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=HTH merR-type domain-containing protein {ECO:0000259|PROSITE:PS50937};
GN ORFNames=M877_02180 {ECO:0000313|EMBL:EST33257.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST33257.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST33257.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST33257.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST33257.1}.
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DR EMBL; AWQW01000019; EST33257.1; -; Genomic_DNA.
DR AlphaFoldDB; V6KMD9; -.
DR STRING; 193462.BBN63_06745; -.
DR PATRIC; fig|1352941.4.peg.449; -.
DR eggNOG; COG0789; Bacteria.
DR HOGENOM; CLU_045945_3_2_11; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR30204:SF96; MERR FAMILY REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 37..103
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 36984 MW; 3071BC4B5C613AC1 CRC64;
MSEPAHAGGT AGGTAGGTAD DIADDIADEA GAVASVSTGT AARRIGVSPI TLRSWDRRYG
IGPARQDGRH RRWTPADLAV LDEMCRLTAA GVPPAEAARA ARERGGGPPP APGVRRPEAG
PGPPLGDVRL ECRGLSRAAL RLDAPVVDEL LTSFVDEYGL VRAWEDLMMP TLRAVGRRWA
SAGDKYVEAE HLLSWHVSSA LRRVPAAPPA RTGAGPVLLA CVPGEQHTLP IEALTAALAE
RGLPTRMFGA AVPATALDEA ARRTGPRAVV LWSQSRSTAS RPLARHIAAG SWGVRGARGS
AEVMLAGPGW AGPPVPGLSR PHGLRDALAT LTRLYGTEHE GRPPCPPHAA PPTSW
//
