ID V6KN11_STRRC Unreviewed; 389 AA.
AC V6KN11;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Cysteine desulfarase {ECO:0000313|EMBL:EST33408.1};
GN ORFNames=M878_12880 {ECO:0000313|EMBL:EST33408.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST33408.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST33408.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST33408.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST33408.1}.
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DR EMBL; AWQX01000105; EST33408.1; -; Genomic_DNA.
DR RefSeq; WP_023546587.1; NZ_CM002285.1.
DR AlphaFoldDB; V6KN11; -.
DR STRING; 1352936.M878_12880; -.
DR PATRIC; fig|1352936.5.peg.2716; -.
DR HOGENOM; CLU_003433_0_0_11; -.
DR OrthoDB; 9808002at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR Gene3D; 1.10.260.50; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984}.
FT DOMAIN 3..372
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 389 AA; 40497 MW; BF7BE201F74C542B CRC64;
MAYLDHAATT PMLPEAAEAL IAQLSITGNA SSLHASGRQA RRTVEESRET LAEALGARPS
EVVFTSGGTE ADNLAVKGLY WSRRDADPAR TRVLASPVEH HAVLDAVHWL GEHEGATVEY
LPVDSYGRVH PEALREAISR NPDDVALVTV MWANNEIGTI LPVRELADVA AEFGIPMHAD
AVQALGQVPV DFAASGLAAM TVSGHKIGGP YGIGALLLGR DHTPVPVLHG GGQERHVRSG
TLDVPAIASF AVAGRLATER RTWFAREIGA LRDQLIAAVR GAVPDAILGG DPAPEGRLPA
NAHFTFPGCE GDSLLLLLDA QGIECSTGSA CTAGVAQPSH VLLATGTDPD LARGTLRFSL
GHTSTEADVE AVAKAIGPAV ERARAAGLS
//
