ID V6KNW8_STRNV Unreviewed; 798 AA.
AC V6KNW8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Hydrolase {ECO:0000313|EMBL:EST33146.1};
GN ORFNames=M877_02540 {ECO:0000313|EMBL:EST33146.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST33146.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST33146.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST33146.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST33146.1}.
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DR EMBL; AWQW01000022; EST33146.1; -; Genomic_DNA.
DR AlphaFoldDB; V6KNW8; -.
DR STRING; 193462.BBN63_02095; -.
DR PATRIC; fig|1352941.4.peg.521; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_009935_3_0_11; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0046556; F:alpha-L-arabinofuranosidase activity; IEA:InterPro.
DR GO; GO:0046373; P:L-arabinose metabolic process; IEA:InterPro.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007934; AbfB_ABD.
DR InterPro; IPR036195; AbfB_ABD_sf.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF2; BETA-MANNOSIDASE; 1.
DR Pfam; PF05270; AbfB; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF110221; AbfB domain; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EST33146.1}.
FT DOMAIN 93..213
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 253..350
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 392..504
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 653..792
FT /note="Alpha-L-arabinofuranosidase B arabinose-binding"
FT /evidence="ECO:0000259|Pfam:PF05270"
FT REGION 49..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 798 AA; 86084 MW; 2BF39314FC7C4E99 CRC64;
MRASLPSSTS THVPTHVPTR FPTRDRATAW IGALLLLCAS LVVAGGGPAE AKPSAWQPKP
SPMTTPWTNQ VPVDNPLPEY PRPQLTRPDW LNLNGLWDFA VTGANAGQPA AFPEQIRVPF
VAESALSGIQ RKITQSDKLW YKRTFTVPAG WNGRRVQLNF GASDWQTTVW VNGSQAGAAH
SGGYDAFTYD ITTLLTAGTN TVVVSVFDPS QTGGQAVGKQ RISDVTPHPG GGIFYTAASG
IWQTVWLEPT ASAHITRLDM VPSLSDNTLK VTVRAAGTAG HTARVTVSSG GTAVATVTGP
VNSPFSVPVP NPRLWSPEDP FLYDIRADLL SGTGGGGTTV DSAGSYAGMR SISVGKVGGV
QRPLLNGKFV FQTGTLDQGY WPDGIYTAPS DEALRHDLQK HKDLGFNMVR KHIKVEPQRW
FYWADRLGLL VWQDMPAMDT RTPDGAARVQ WEAEYDRIID QHRSSPSLVM WVNQNEGWGQ
YDQARIADEV KAYDPTRLVN NMSGVNCCGS VDGGNGDVID NHVYVGPGTT TPTATRAAVL
GEFGGLGWKV PGHEWYPGGG FSYEDQASVA ALNNRFVGLI DTIRENQMPS GLSASVYTEI
TDVENEANGL LTYDRQVVKV DAARVRAANL ALVDASRNPP PPVTLPTGQN KSLRVTTPGH
TGKYLRHQDG LAFTAPVDAN SDSLLKNDAT WKIVPGLAGS GCYSFESRNY PGQYLRHRDF
RVYKEAGDGS ALFRADATFC ALPAAGGVRL AAYNMAGGYL RHINSEVWMA TRGGPRAWDN
PASFTEDTTW AVADPWAG
//
