ID V6KP82_STRNV Unreviewed; 661 AA.
AC V6KP82;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:EST33932.1};
GN ORFNames=M877_00430 {ECO:0000313|EMBL:EST33932.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST33932.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST33932.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST33932.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST33932.1}.
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DR EMBL; AWQW01000003; EST33932.1; -; Genomic_DNA.
DR RefSeq; WP_023536410.1; NZ_CM002280.1.
DR AlphaFoldDB; V6KP82; -.
DR STRING; 193462.BBN63_33900; -.
DR PATRIC; fig|1352941.4.peg.89; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_009935_2_1_11; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF3; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 37..139
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 203..305
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 339..470
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 661 AA; 73211 MW; 8815523B441593D1 CRC64;
MSLPPAGPSD SLSDQSNTVP RPEYPRPSFV REEWRNLNGT WQFAFDPGDS GLERGLVHRE
FDGRIVVPFC PESELSGIGD PDFHPAVWYR RTVRVPAHWA GRRVLLHFGA VDHDATVWAD
GREVARHSGG FTSFTVDLGD VAGSSAAGPG ADGEVVVVVR ARDNPHGPQA RGKQSVEYAN
SACHYTRVTG IWQTVWMEPV ADVRLERPRI TPDLGSGAFH LDLPLSANRP GHRVRAVLRD
ADGDIVVRAE VRADLDLAPR MVLTVPADRL RPWSPSDPHL YSALIELVDA AGQVTDSAVC
TAGLRSVAID GKRLLLNGHP VFQRLVLDQG WYPDGLMTAP DDAALVRDIE LSLAAGFNGA
RLHQKVFEER FLHHADRLGY LVWGEFGDWG CASGTTTRDN QRPTAGYTAQ WLEALERDYS
HPSIVGWCPL NETHQKLHDR QSVLDDVTRS MFLATKAADR SRPVIDASGY SHRVAETDVY
DSHSYEQDPA LFRAQMAGLD KDAPFVNPDE RDTDAVWSLP YRGQPYFCSE FGGIWWNPEE
AAAHRDGPDG DAGVDDADRS VSWGYGQRPR TEEEFQRRFA GLTGVLLDDP HMFGYCYTQL
TDVFQEQNGV YRFDRTPKLD VGRLRVAQER RAAFEGPAFE GPAGAAAVGE DRDDGIDGDE
R
//
