ID V6KP99_STRNV Unreviewed; 299 AA.
AC V6KP99;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=HTH lysR-type domain-containing protein {ECO:0000259|PROSITE:PS50931};
GN ORFNames=M877_00905 {ECO:0000313|EMBL:EST33843.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST33843.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST33843.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST33843.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST33843.1}.
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DR EMBL; AWQW01000004; EST33843.1; -; Genomic_DNA.
DR RefSeq; WP_023536505.1; NZ_CM002280.1.
DR AlphaFoldDB; V6KP99; -.
DR PATRIC; fig|1352941.4.peg.187; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_4_11; -.
DR OrthoDB; 79118at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08414; PBP2_LTTR_aromatics_like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
FT DOMAIN 1..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 299 AA; 32143 MW; 69F5D7698739DBBC CRC64;
MDVHGRDLRY FVAVAEELHF TRAAERLFVS QPALSKQLRM LERTLGAPLF DRDRHGVRLT
SAGAALLPHA RRVLADWDTG LVAFEEAKAA QRATLAVGMS TSPGRGGMLP AIRSRFAAAH
PEAVLTLHQV NWSDTTAGLA DGASDVAFVW LPLPGAARYR WTVMAEEPRL VAMAESHRLA
ARETVDFPDL LDEPFLALPE SAGPLRDHWL ATDTRDGRPP VIGAEIASPD ETYEALVDGL
GVCLLAAGNA PLVARAGVVT RPVAGLPPAQ LALAWRADDN RPLVRAYVEA ARATHGPTA
//
