ID V6L1C1_9ACTN Unreviewed; 369 AA.
AC V6L1C1;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:EST37511.1};
GN ORFNames=N566_12670 {ECO:0000313|EMBL:EST37511.1};
OS Streptomycetaceae bacterium MP113-05.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae.
OX NCBI_TaxID=1380770 {ECO:0000313|EMBL:EST37511.1, ECO:0000313|Proteomes:UP000017915};
RN [1] {ECO:0000313|EMBL:EST37511.1, ECO:0000313|Proteomes:UP000017915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP113-05 {ECO:0000313|EMBL:EST37511.1,
RC ECO:0000313|Proteomes:UP000017915};
RA Valde M., Degnes K.F., Sletta H., Ruckert C., Kalinowski J., Zotchev S.B.;
RT "Streptomyces bacterium from a marine sponge: physiological
RT characterization and genome-based analysis of secondary metabolite
RT biosynthesis potential.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST37511.1}.
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DR EMBL; AWQV01000414; EST37511.1; -; Genomic_DNA.
DR AlphaFoldDB; V6L1C1; -.
DR STRING; 1380770.N566_12670; -.
DR PATRIC; fig|1380770.3.peg.2197; -.
DR HOGENOM; CLU_037628_6_1_11; -.
DR Proteomes; UP000017915; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000017915};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 17..71
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 349..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 39136 MW; 2D7CE4A86D737016 CRC64;
MSRSSPAQAG RRRQSRAGIR DVAAAAGVSI TTVSDALNGK GRLPDTTRSH VRAVAERLGY
RPSAAARTLR TGKSGLVGLT VTTYGEEPFT FTEFAYFAEM ARSATSAALA RGYALVILPA
ASRHSAFDIW SNVALDGTVV IDPSDHDPLV TELVRSGIPV VSDGRPADSL PVTAWVDNDH
EAAVRGLLDH LAESGARRIG LLTGTSTDTY TRLSTSAYLD WCERVGQEPV VEAYPAHDPA
AGAVAADRLL ARPDRPDAVY GLFDPNGTDL LAAARRYGLR VPEDLLLVCC SESSVYAGTE
PPITTLSLKP GRIGNTVIQL LIDAIESGGP VSGTRPVEQV MPTDLIVRTS SRRRPPRTTV
SAPRGPTSE
//
