ID V6L4R5_STRRC Unreviewed; 357 AA.
AC V6L4R5;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=HTH lacI-type domain-containing protein {ECO:0000259|PROSITE:PS50932};
GN ORFNames=M878_02965 {ECO:0000313|EMBL:EST36209.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST36209.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST36209.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST36209.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST36209.1}.
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DR EMBL; AWQX01000019; EST36209.1; -; Genomic_DNA.
DR RefSeq; WP_023544617.1; NZ_CM002285.1.
DR AlphaFoldDB; V6L4R5; -.
DR STRING; 1352936.M878_02965; -.
DR PATRIC; fig|1352936.5.peg.653; -.
DR HOGENOM; CLU_037628_6_1_11; -.
DR OrthoDB; 252678at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..64
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 357 AA; 37108 MW; AB9A23D1F3CCAD59 CRC64;
MTTSHGARRP TIADVAAAAS VSRTTVSHAL NGIGKVDPRT RERIKKIAAE LGYRPNLRAQ
RLRRGEAKAI ALASSMPFAV AGGPSRLGFY MEVAAAAAER ALVHGYALVL IPPVQSGSAL
YSVDIDGAIV VEPEAHDAAV AQLRERGLPY VALGRPTAPE DDAPYVDLHG GSVVDLLLEH
LRDQGARSPA LVIGAGTRHS SVDARAAYER AAAAHGWPPI VVTAPENGGE QAGYDSCAAL
LAQHPGIDAL CVLVDAFAVG AVRALRAAGR RIPDDVMVVT RYDGLRARTC EPPLTAVDLG
LERAASDAVE LLLARLGARP ATGVAGAAEC GGEVPAAEPL LVPRASSLRR APFAERD
//
