ID V6LFU7_9EUKA Unreviewed; 1115 AA.
AC V6LFU7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Helicase {ECO:0000313|EMBL:EST43377.1, ECO:0000313|EMBL:KAH0571028.1};
GN ORFNames=SS50377_17057 {ECO:0000313|EMBL:EST43377.1}, SS50377_27322
GN {ECO:0000313|EMBL:KAH0571028.1};
OS Spironucleus salmonicida.
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Hexamitinae;
OC Spironucleus.
OX NCBI_TaxID=348837 {ECO:0000313|EMBL:EST43377.1};
RN [1] {ECO:0000313|EMBL:KAH0571028.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 50377 {ECO:0000313|EMBL:KAH0571028.1};
RX PubMed=24516394;
RA Xu F., Jerlstrom-Hultqvist J., Einarsson E., Astvaldsson A., Svard S.G.,
RA Andersson J.O.;
RT "The Genome of Spironucleus salmonicida Highlights a Fish Pathogen Adapted
RT to Fluctuating Environments.";
RL PLoS Genet. 10:E1004053-E1004053(2014).
RN [2] {ECO:0000313|EMBL:EST43377.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu F., Jerlstrom-Hultqvist J., Einarsson E., Astvaldsson A., Svard S.G.,
RA Andersson J.O.;
RT "The Genome of Spironucleus salmonicida Highlights a Fish Pathogen Adapted
RT to Fluctuating Environments.";
RL PLoS Genet. 0:0-0(2014).
RN [3] {ECO:0000313|EMBL:KAH0571028.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 50377 {ECO:0000313|EMBL:KAH0571028.1};
RA Xu F., Kurt Z., Jimenez-Gonzalez A., Astvaldsson A., Andersson J.O.,
RA Svard S.G.;
RT "New Spironucleus salmonicida genome in near-complete chromosomes.";
RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI546139; EST43377.1; -; Genomic_DNA.
DR EMBL; AUWU02000007; KAH0571028.1; -; Genomic_DNA.
DR AlphaFoldDB; V6LFU7; -.
DR EnsemblProtists; EST43377; EST43377; SS50377_17057.
DR VEuPathDB; GiardiaDB:SS50377_27322; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000018208; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EST43377.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018208}.
FT DOMAIN 83..239
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 308..513
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1115 AA; 124351 MW; AA84B70B0A148F28 CRC64;
MEFDLLTTPA AMSTAESRPL PTIIEVPQPI PANPLKAIRH SVVFPPETTP PASLSADIFT
LPPVANPAKT FPFTLDPFQE KAIAALNRGE SVMVSAHTSA GKTAIAEYAI SICVQRGQKV
AYTSPIKALS NQKFRDLSLT YDSVGLLTGD STVNKQAQIL VMTTEILRNM LQQGGELLRE
LGCVVFDEVH YMRNAERGVV WEDCISQLNS KMTFVFLSAT IPNAAEFAGW VCSIHGKPMH
VIYTEFRPVP LQFCICPIGG TEVFHAFSSD DRQLNTANIA KARQMLPFQG GKQGGMTGKL
KQKMMNETIL TCLKMLKSKQ ILPVIVFSFG KARCEELAQM LLKEGQIGSL LSQSQQDAVE
LIFSAALREI DPADQQLKQI VQARQLLLRG VAVHHSGLLP FVKEVTEILF QEDLVKVIFV
TETFAMGLNL PARCVVFTDL QKYDGQQNRY VQSGEFIQMA GRAGRRGLDT QGVVISFFAS
QDDCSASLDV MRGGAEALNS SYKIGYSQLV NYLRIEGFSA EQAISRSFLQ FQRDFRLPRC
ANSLYQIEIA LLQFEKQFSD AATGLALPET LQFLDLEELK FREMLKLMEM GREPQLEKQL
VSRLVRGRIL QISGDGQNFG PCVLLGSSVQ GGALFLDVLA PLVAPKQYNA AKRSSEPAAV
LNSCKSRDFA PSDRFVEDLL QNSEFSSFLS PKTADLDDIL AENASNLVGL SDSELCRPEF
KCCETVSHEI NQKMNNLTSN CVFRFIMERK NVHYQTILFD KANFVPIVFR VPISCVSEIS
TVYVKNLPVS AADYDDRKLI LTKFMAVLVQ LFERQKGDLE EVFVFRDDII PKLQFDQLEN
INVKYVEQQQ RVQKIQELLK TNFYSYYKYF NDYYIKSGNI HEILLQILKL KRRQNLLSNE
LKSGSKVLVE DLKNKKLLLQ HLKYFDFESQ TALEKGKIAS KINAVNELIV VEAIFGNLFS
DASVPVFCGV VCALLGERVR GQEAALSAEL EAPLQRLTDV VSGLLDACAV YGVELETGIT
RSDELVDRNA AQAAFLWADQ RSLQEILDEI PSLFEGSVVR MFRRLVTGLE QVQEAVAGWG
DGALSTKCAD AIKVVNRGLV RADSLYIIDE QPQED
//
