ID V6M546_9BACL Unreviewed; 480 AA.
AC V6M546;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN Name=gabD {ECO:0000313|EMBL:EST53689.1};
GN ORFNames=T458_23275 {ECO:0000313|EMBL:EST53689.1};
OS Brevibacillus panacihumi W25.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=1408254 {ECO:0000313|EMBL:EST53689.1, ECO:0000313|Proteomes:UP000017973};
RN [1] {ECO:0000313|EMBL:EST53689.1, ECO:0000313|Proteomes:UP000017973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W25 {ECO:0000313|EMBL:EST53689.1,
RC ECO:0000313|Proteomes:UP000017973};
RX PubMed=24459276;
RA Wang X., Jin D., Zhou L., Wu L., An W., Chen Y., Zhao L.;
RT "Draft Genome Sequence of Brevibacillus panacihumi Strain W25, a
RT Halotolerant Hydrocarbon-Degrading Bacterium.";
RL Genome Announc. 2:e01215-13(2014).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST53689.1}.
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DR EMBL; AYJU01000017; EST53689.1; -; Genomic_DNA.
DR RefSeq; WP_023558449.1; NZ_KI629785.1.
DR AlphaFoldDB; V6M546; -.
DR STRING; 1408254.T458_23275; -.
DR PATRIC; fig|1408254.3.peg.4572; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_5_1_9; -.
DR OrthoDB; 20170at2; -.
DR Proteomes; UP000017973; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000017973}.
FT DOMAIN 13..476
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 249
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
FT ACT_SITE 283
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 480 AA; 52456 MW; 246EDD52A823118B CRC64;
MGESKQMYIN GEWVSAESGE TLAVINPATC EQVGTVSFGD AREAKKAIDA AHEAFQSWSR
LTARERSKYL STLAELVRKN RDELAGLISA EMGKPLGEAK GEVLGAADNF VWYSEEAKRV
YGETIPSSVA NKRIMVLRQP VGVVGAITPW NFPINMVVRK IAPALAAGCT VVLKPAESTP
LTAVRLFELI EQAGFPKGVV NLVVGNAESV GGEFLDNPKL SKIAFTGSTR VGKLLMEGAA
KQVKRVSMEL GGHAPFIVFA DADLDAAVKG LFESKFRNSG QMCICTNRLY VHEEVADAFT
EKLVERLKRA KVGDGREKET EIGPLVNERA LNKVLEHIED ARDKGAHVVF GGNRMTEGDY
AKGFFCEPTV ISNVTTDMKI TYEETFGPVV PIVRFTDEAE VVRQANDTRY GLAAYVYTRD
NQRCFRMAEE LEYGIVGIND GSPTQTQAPF GGFKESGIGR EGGRFGMDEY LETKFVSFGL
//
