ID V6TG56_GIAIN Unreviewed; 631 AA.
AC V6TG56;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ankyrin repeat protein {ECO:0000313|EMBL:ESU37923.1};
GN ORFNames=DHA2_150701 {ECO:0000313|EMBL:ESU37923.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU37923.1, ECO:0000313|Proteomes:UP000018320};
RN [1] {ECO:0000313|Proteomes:UP000018320}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DH {ECO:0000313|Proteomes:UP000018320};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU37923.1, ECO:0000313|Proteomes:UP000018320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH {ECO:0000313|EMBL:ESU37923.1,
RC ECO:0000313|Proteomes:UP000018320};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU37923.1}.
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DR EMBL; AHGT01000019; ESU37923.1; -; Genomic_DNA.
DR AlphaFoldDB; V6TG56; -.
DR EnsemblProtists; ESU37923; ESU37923; DHA2_150701.
DR VEuPathDB; GiardiaDB:DHA2_150701; -.
DR VEuPathDB; GiardiaDB:GL50581_222; -.
DR VEuPathDB; GiardiaDB:GL50581_544; -.
DR VEuPathDB; GiardiaDB:GL50803_0061420; -.
DR VEuPathDB; GiardiaDB:QR46_1274; -.
DR Proteomes; UP000018320; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR PANTHER; PTHR24120; GH07239P; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 6.
DR SMART; SM00248; ANK; 15.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 9.
DR PROSITE; PS50088; ANK_REPEAT; 9.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT REPEAT 134..155
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 196..228
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 265..288
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 327..359
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 358..390
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 389..421
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 449..481
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 480..512
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 511..543
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 69502 MW; 69B6EBB512538725 CRC64;
MHLARRENEN CTWPGEKIKM AQSDVDRRRV ESGGPPSPSG GVTELMQTAK DGTEDVKGLL
GTRFNLICRQ DNHGQTALMW VAGYSPIEAI KSVLERGKDV KGDQDHSALR HALNDGRLEV
TRVIISYEDP TDRNGVTALM RAAARGDTEM VRLLVPIQGG MKDGAGETAL MSTARNGHVE
CLKLLLDKEE GMQRPDGWTA LMMAALRGHA ECVKLLLEKE GGMQRRSLVN AAENGDTDAE
MMELLPLQER KKAEGGVKID RWRMTGGTAL MTAAEYGHAD VVRLLVSREG GKYDNNHKTA
LMFAAQNGRT ECARLLLEKE EGMKDSNDKT ALMWAAQNGR TECVKLLLEK EARMKDSDGK
TALMFAAQNG HQDCVKLLLE KEGGMQKSDG STALMFAAEE GHTDCVRLLC EHKSERDASG
WTNLMCAACI GDADAVRSNL QQAGVHDGRG YTALMWAAQN GRTECVKLLL EKEARMKDSD
GKTALMFAAQ NGHQDCVKLL LEKEGGMQKS DGSTALMFAA EEGHTDCVRL LCEHKSERDA
SGWTNLMCAA CIGDADAVRR NIQETKRTDK YGWTALMWAV CNRKPGCVRL LKDREKDLRS
TREFIGFEAG TTALDIANEL IYEEIIEILS E
//
