ID V6THZ3_GIAIN Unreviewed; 660 AA.
AC V6THZ3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 28-JUN-2023, entry version 21.
DE RecName: Full=PHD-type domain-containing protein {ECO:0000259|PROSITE:PS51805};
GN ORFNames=DHA2_153362 {ECO:0000313|EMBL:ESU36560.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU36560.1, ECO:0000313|Proteomes:UP000018320};
RN [1] {ECO:0000313|Proteomes:UP000018320}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DH {ECO:0000313|Proteomes:UP000018320};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU36560.1, ECO:0000313|Proteomes:UP000018320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH {ECO:0000313|EMBL:ESU36560.1,
RC ECO:0000313|Proteomes:UP000018320};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU36560.1}.
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DR EMBL; AHGT01000044; ESU36560.1; -; Genomic_DNA.
DR AlphaFoldDB; V6THZ3; -.
DR EnsemblProtists; ESU36560; ESU36560; DHA2_153362.
DR VEuPathDB; GiardiaDB:DHA2_153362; -.
DR VEuPathDB; GiardiaDB:GL50581_3473; -.
DR VEuPathDB; GiardiaDB:GL50803_0016232; -.
DR VEuPathDB; GiardiaDB:QR46_3646; -.
DR Proteomes; UP000018320; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00249; PHD; 1.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 604..656
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
SQ SEQUENCE 660 AA; 74000 MW; C902E8230B10EF73 CRC64;
MEGHEANIST NVRAVRPFVP GVVVHYTLSD VQDMGIIASI TELSPALRES YYGDSHELTC
LVRSEDQGGL VYYSIPGKDI SLATRDSLTG APQTPTVVSF LSLLNIGEIC PEQVFGQHVL
IYHPTYKSPS PCGTLGVPLS PMFLTSINHS FTLRYLKTLA LKLQREPTLL CLRDLWRFLT
LHDYDQKLEE PDPKDTFTCR TPSVANYSTK GSDTLGNFII NEYSRCYNIH GVELSVGDIC
RVTGALQPVR IDRILEMGPN GTGGHATDQK IYIYGLTYLS DSRSTSDIVP CVYPVSLVEQ
LVSTDSTSFA EEFQIDSDVY DLWTLVTAEH IQEENHYIAT IDMQTGFNFV SALDVYLSPN
DAEVTYATPI ECSLCRYLYV QGNIYKIPTG EHVASWKHGR DGSVTIHEQD PNSEPSPVSF
FDLRKSYDAE QSVVTQEPWL YTASCTYTYS KVTDRSLNEL LELAGRILER TSDIAVARKF
QCCYCGNVLT GEDRVAGPFI YALVKCPTPL FLAQYVPPVL FVAHHSCAFY TPEVAFLKAK
DLKSEHTRIL SEKRFDLTVA KRVTRNQTPI PLIVQATALD RVLRALLTEF SPRVYLNFRK
TFKKNRIELS CSICGKPGAL IGCYNKSCQF TAHYPCVVSK GLVITEKREM YCKRHSRCST
//
