ID V6TWT0_GIAIN Unreviewed; 351 AA.
AC V6TWT0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Replication factor C subunit {ECO:0000313|EMBL:ESU43054.1};
GN ORFNames=GSB_9287 {ECO:0000313|EMBL:ESU43054.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU43054.1, ECO:0000313|Proteomes:UP000018040};
RN [1] {ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GS {ECO:0000313|Proteomes:UP000018040};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU43054.1, ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS {ECO:0000313|EMBL:ESU43054.1,
RC ECO:0000313|Proteomes:UP000018040};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family.
CC {ECO:0000256|ARBA:ARBA00005378}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU43054.1}.
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DR EMBL; AHHH01000061; ESU43054.1; -; Genomic_DNA.
DR AlphaFoldDB; V6TWT0; -.
DR EnsemblProtists; ESU43054; ESU43054; GSB_9287.
DR VEuPathDB; GiardiaDB:DHA2_9287; -.
DR VEuPathDB; GiardiaDB:GL50581_1303; -.
DR VEuPathDB; GiardiaDB:GL50803_009287; -.
DR VEuPathDB; GiardiaDB:QR46_2065; -.
DR eggNOG; KOG0989; Eukaryota.
DR Proteomes; UP000018040; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR PANTHER; PTHR11669:SF20; REPLICATION FACTOR C SUBUNIT 4; 1.
DR Pfam; PF00004; AAA; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
FT DOMAIN 35..171
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 351 AA; 39624 MW; 92881B736D470419 CRC64;
MSAPWTEKHR PLALDRIVHQ DHAVRAAKRC IESGNMPHML LYGPAGTGKT TLVHAMMHEF
FGPRFWRARV NEFNASTDRG IKIVRERIKS IARTVIAVAP EDVKALYPCP DFQVIVLDEA
DALTRESQAA LRRIIEDYSE TTRFCILCNY PSQIIAPIVS RCARFAFSPL PQTLIIDRLT
AICYAEMHQL RNANEQLSQL ASDALREVAI LSQGDMRAAI TLLQTTVQFC QSMGEELSPE
HVRLLAGKIP DELIASLIEK MTDVSLPVES LMEYLHKSVI RTGYPALDVI RELWRSLCFE
AQAPESLRYA VGDAYQRAGL YVARRVSDAS VLERFVLAIY NSYCRLNQKS V
//
