ID   V6Z7D6_STRAG            Unreviewed;       482 AA.
AC   V6Z7D6;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Guanine permease {ECO:0000313|EMBL:ESV55539.1};
GN   ORFNames=SAG0136_10150 {ECO:0000313|EMBL:ESV55539.1};
OS   Streptococcus agalactiae LMG 14747.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1154860 {ECO:0000313|EMBL:ESV55539.1, ECO:0000313|Proteomes:UP000018482};
RN   [1] {ECO:0000313|EMBL:ESV55539.1, ECO:0000313|Proteomes:UP000018482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 14747 {ECO:0000313|EMBL:ESV55539.1,
RC   ECO:0000313|Proteomes:UP000018482};
RA   Richards V.P., Durkin S.A.S., Kim M., Pavinski Bitar P.D., Stanhope M.J.,
RA   Town C.D., Venter J.C.;
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESV55539.1}.
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DR   EMBL; ANQC01000135; ESV55539.1; -; Genomic_DNA.
DR   AlphaFoldDB; V6Z7D6; -.
DR   eggNOG; COG2252; Bacteria.
DR   Proteomes; UP000018482; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        48..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        198..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        222..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        278..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        424..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   482 AA;  50218 MW;  648FC0B2BB3637BC CRC64;
     MEKLFKLKEH GSTVRTEIVA GLTTFFAMSY ILFVNPSILG AAGMPTQAVF LATIISSVIS
     TLIMGLFANV PYALAPGMGL NAFFTYTVVF GLGFSWQEAL AMVFICGLFN IFITVTKVRK
     SIIKAIPVSL QHAIGGGIGV FVAYLGFKNA NIIDFSLSAD NIVAINGAAP ASADLSKGVS
     SIAANGGVVP AISTFTDPAV ILAVIGLFLT AILVIKNVRG AILIGIIVTT LLGIPMGVVD
     LSSVSFSNNL ASAFGELGTT FLAAFDGMGS LFSDSTRLPL VLMTIFAFSL SDTFDTLGTF
     IGTGRRTGIF SVEDEASLEN SSGFSSKMDR ALFADAIGTS IGALFGTSNT TTYVESAAGI
     AEGGRTGLTA VSTAVAFLLS VFLLPLIGIV PAAATAPALI IVGVMMVSSF LDVDWSNFED
     ALPAFFAAFF MALCYSISYG IAAAFIFYCL VKVVKGKASD IHPILWGATA LFVLNFVILA
     IL
//