ID   V7AF24_PHAVU            Unreviewed;       818 AA.
AC   V7AF24;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   28-FEB-2018, entry version 17.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=PHAVU_011G071600g {ECO:0000313|EMBL:ESW04162.1};
OS   Phaseolus vulgaris (Kidney bean) (French bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae;
OC   Phaseoleae; Phaseolus.
OX   NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW04162.1, ECO:0000313|Proteomes:UP000000226};
RN   [1] {ECO:0000313|EMBL:ESW04162.1, ECO:0000313|Proteomes:UP000000226}
RP   NUCLEOTIDE SEQUENCE.
RA   Schmutz J., McClean P., Shu S., Cregan P., Rokhsar D., Jackson S.;
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; CM002298; ESW04162.1; -; Genomic_DNA.
DR   RefSeq; XP_007132168.1; XM_007132106.1.
DR   EnsemblPlants; ESW04162; ESW04162; PHAVU_011G071600g.
DR   GeneID; 18615425; -.
DR   Gramene; ESW04162; ESW04162; PHAVU_011G071600g.
DR   KEGG; pvu:PHAVU_011G071600g; -.
DR   KO; K02154; -.
DR   Proteomes; UP000000226; Chromosome 11.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000226};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    418    445       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    466    484       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    547    565       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    585    602       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    637    654       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    755    776       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       99    119       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   818 AA;  93701 MW;  E9B7A4B0E4F574B9 CRC64;
     MNRFIENLPP MDLMRSEKMT FVQLIIPAES SHRAITYLGE LGLIQFRDLN AEKSPFQRTF
     VNQVKRCAEM SRKLRFFKDQ INKAGLMSSP SVLQSDIHLE DLEIQLAEHE YELIEMNSNS
     EKLRKSYNEL LEFKIVLEKA CSFLVSSRGA VVPEERELEE NVFSHGNYVE TPFLFEQEIT
     PAPSNQSGLR FISGIICKSK VLRFERMLFR ATRGNMLFNQ APADEHIIDP ISTEMVEKTV
     FVVFFSGEQA RIKILKICDA FGANCYPVPE DISKQRQITS EVSARLADLE ATLEAGIRHR
     NKALASVGGP LTIWMDMVKR EKSVYDTLNM LNFDVTKKCL VGEGWCPVFA KTQIQEALQR
     ATFDSNSEVG IIFHSMDALE SPPTYFRTNS FTGPYQEIVD AYGVARYQEA NPAVYTTIIF
     PFLFAVMFGD WGHGICLLLG ALVLIARENK LSTQRLGSFM EMLFGGRYVL LLMSLFSIYC
     GLIYNEFFSV PYHIFGASAY KCRDNTCRDA HTTGLVKYRE PYPFGVDPSW RGSRSELPFL
     NSLKMKMSIL FGVVHMNLGI ILSYFNAHFF GSLLDIRYQF VPQMIFLNCL FGYLSLLIIV
     KWCTGSQADL YHVMIYMFLS PFENLGDNQL FWGQRPLQVL LLLLSVIAVP WMLFPKPFML
     KKLHNERFQG RTYGVLHTSE VDLELEPGSA RQHDDDFNFT EVFVHQMIHS IEFVLGSVSN
     TASYLRLWAL SLAHSELSTV FYEKVLLLAW GYDNLVVRLV GLAVFSFATA FILLMMESLS
     AFLHALRLHW VEFQNKFYHG DGCKFRPFSF ASLTEDEN
//