ID V7C6L2_PHAVU Unreviewed; 1079 AA.
AC V7C6L2;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=PHAVU_004G140100g {ECO:0000313|EMBL:ESW24551.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW24551.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
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DR EMBL; CM002291; ESW24551.1; -; Genomic_DNA.
DR RefSeq; XP_007152557.1; XM_007152495.1.
DR AlphaFoldDB; V7C6L2; -.
DR STRING; 3885.V7C6L2; -.
DR EnsemblPlants; ESW24551; ESW24551; PHAVU_004G140100g.
DR GeneID; 18633007; -.
DR Gramene; ESW24551; ESW24551; PHAVU_004G140100g.
DR KEGG; pvu:PHAVU_004G140100g; -.
DR OMA; AMGHIVM; -.
DR OrthoDB; 905172at2759; -.
DR Proteomes; UP000000226; Chromosome 4.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11017:SF431; NB-ARC DOMAIN PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000226}.
FT DOMAIN 9..176
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 1079 AA; 123432 MW; 26EE37E8316402BC CRC64;
MATTTSHGFT YDVFLSFRGE DTRYAFTANL FKALDDKGIH SFFDDDKLES GEEITATLVK
AIEESRIAIV VLSPNYASSS FCLDELATIL HCKTKGLFVI PVFYKVDPSH VRHQKGSYGE
ALAEHQKRFK DKKEKLQKWK VALRQVADLS GYHFKDGDEY QYNFIGRIVE RVSREINRAP
LHVADHPVGL LSQVLKVKKL LDVGSNDVVH IIGIHGMGGI GKTTLALEAY NLIVDDFDGS
CFLQNVRVES NKHGLKHLQA LILSEILGEK NINLASVQRG ISMIQQRLRR KKVLLILDDV
DNRKQLQAFA GRSDWFGPGS RVIVTTRDEQ LLKSHKVERT YEVEELNKYD SLQLLIWNAF
KRANFDPSYE DVLKRVVTYA SGLPLALEVI GSNLVGKSVE EWESAIEHYK RIPNGEILEI
LKVSFDALGE EEKSVFLDIA CCFKGSNLTE VEHILGVLYD NNMKHHIGVL VEKSLIKVKV
WRSVVEMHDL IEDMGRQIDQ QKSPKEPGKH RRLWLPKDII HVLKHNTGTS RIKIICLDLS
IREKEETLEW NANAFKRMKN LKILIIRNGK FSKGPNYFPE SLSVLEWHGY PSNCLPSNFL
PNNLVICKLT DSSLVSFGFH GSLKASLKSK FENLTVLNFD QCKYLTQIPD MSDLPNLEEV
SFKKCGSLIA VHDSIGFMTK LKILNAEGCI KLMSFPPLNL PTLESLKLSY CSNLEKFPEI
LGKMGNIRVL QLEELPIKEL PVSFQNLIRL RDLILSCEIV HLPSSIVMMP ELLDICVTNC
KEWQWLKSDE GEDNIGSMVS SKVDWFFASS CNLDDQFFSA GFMQLAQVRS LFLRENNFKF
LPECIKEFHN LHTLDVSHCK HLQEIRGVPP KLKYFKAINC ISLSSSSSSM LLNKRLHEAR
KTEFWFSGTS IPEWFDHQSS GPSSSFWFRN KFPSKVLSLL IAPVGDTDEF DFIRPMVFID
GKVQESKFFC FHKIERMFEL DQTYLFDLQI VPVYGNLFEL PLGNEWKHME VTYEGVIKAS
IVKATGIHVF KEENNIMEDI WFDDYYSNKK IDKDLNGSQS QNHSLLQSIV WEPTHLGYE
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