ID V7CES9_PHAVU Unreviewed; 521 AA.
AC V7CES9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Peroxisomal membrane protein PEX14 {ECO:0000256|ARBA:ARBA00029502, ECO:0000256|RuleBase:RU367032};
DE AltName: Full=Peroxin-14 {ECO:0000256|ARBA:ARBA00029691, ECO:0000256|RuleBase:RU367032};
GN ORFNames=PHAVU_003G200200g {ECO:0000313|EMBL:ESW27421.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW27421.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- FUNCTION: Component of the PEX13-PEX14 docking complex, a translocon
CC channel that specifically mediates the import of peroxisomal cargo
CC proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms
CC a large import pore which can be opened to a diameter of about 9 nm.
CC Mechanistically, PEX5 receptor along with cargo proteins associates
CC with the PEX14 subunit of the PEX13-PEX14 docking complex in the
CC cytosol, leading to the insertion of the receptor into the organelle
CC membrane with the concomitant translocation of the cargo into the
CC peroxisome matrix. {ECO:0000256|RuleBase:RU367032}.
CC -!- SUBCELLULAR LOCATION: Peroxisome membrane
CC {ECO:0000256|RuleBase:RU367032}.
CC -!- SIMILARITY: Belongs to the peroxin-14 family.
CC {ECO:0000256|ARBA:ARBA00005443, ECO:0000256|RuleBase:RU367032}.
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DR EMBL; CM002290; ESW27421.1; -; Genomic_DNA.
DR RefSeq; XP_007155427.1; XM_007155365.1.
DR AlphaFoldDB; V7CES9; -.
DR STRING; 3885.V7CES9; -.
DR EnsemblPlants; ESW27421; ESW27421; PHAVU_003G200200g.
DR GeneID; 18635482; -.
DR Gramene; ESW27421; ESW27421; PHAVU_003G200200g.
DR eggNOG; KOG2629; Eukaryota.
DR OMA; FHWSHAI; -.
DR OrthoDB; 358337at2759; -.
DR Proteomes; UP000000226; Chromosome 3.
DR GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016560; P:protein import into peroxisome matrix, docking; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025655; PEX14.
DR InterPro; IPR006785; Pex14_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23058; PEROXISOMAL MEMBRANE PROTEIN PEX14; 1.
DR PANTHER; PTHR23058:SF0; PEROXISOMAL MEMBRANE PROTEIN PEX14; 1.
DR Pfam; PF17733; DUF5572; 1.
DR Pfam; PF04695; Pex14_N; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367032};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140, ECO:0000256|RuleBase:RU367032};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU367032};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU367032}.
FT DOMAIN 56..100
FT /note="Peroxisome membrane anchor protein Pex14p N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF04695"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 56956 MW; BC368E6070137F07 CRC64;
MATQSPPPPP TPTATDENQG SEIVQPANMN LQNTREEEPA KPSSTPSVFV NSQPLREDQV
QNAVKFLSHP KVKGSPVLYR RSFLEKKGLT KEEIDEAFRR VPDSAPTVQT GGVNQDGQLK
SSSNNQQQTQ QKTLQPISPA STGVNTSSGT LPHSRFHWSH ALIAVGLLAA SGAGTAIIIK
KSFLPRLKSW IRKVVLDNDD EQLKKTDDKP TLMEEAAQAA KSAAAAAAEV AKVSQEILAS
KGEERRYFVE VVSLLDVQVQ EMKSMTNAIR RLEGQEDLRI SQTSSKQLIV NGKADHDLRS
VRSSSPPASV EPSSGLHPKS YMEIMAMVQR GEKPSNIRDI SDLPPNPSQQ PSNPLLVPRS
KPWEVGQVQS TSTQMLQSQV NGEDLNTKTQ DTSLVNGDDP LPWWQRKNVR ITEIDNENES
NGVPFAAASS QQPVQRVWVP PQPPPIAMAG AAEAIRRPKQ VAQKEQMSDN QSVAHSSDSS
DDVQRVSKLL ESEGAVESSS VSSVPRSSEI QEENEVKYDE K
//
