ID V7CF40_PHAVU Unreviewed; 644 AA.
AC V7CF40;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Peptidase A1 domain-containing protein {ECO:0000259|PROSITE:PS51767};
GN ORFNames=PHAVU_002G014200g {ECO:0000313|EMBL:ESW28744.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW28744.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447, ECO:0000256|RuleBase:RU000454}.
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DR EMBL; CM002289; ESW28744.1; -; Genomic_DNA.
DR RefSeq; XP_007156750.1; XM_007156688.1.
DR AlphaFoldDB; V7CF40; -.
DR STRING; 3885.V7CF40; -.
DR MEROPS; A01.A59; -.
DR EnsemblPlants; ESW28744; ESW28744; PHAVU_002G014200g.
DR GeneID; 18636616; -.
DR Gramene; ESW28744; ESW28744; PHAVU_002G014200g.
DR KEGG; pvu:PHAVU_002G014200g; -.
DR eggNOG; KOG1339; Eukaryota.
DR OMA; YQLVEWN; -.
DR OrthoDB; 335768at2759; -.
DR Proteomes; UP000000226; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd05476; pepsin_A_like_plant; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR034161; Pepsin-like_plant.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR032799; TAXi_C.
DR InterPro; IPR032861; TAXi_N.
DR PANTHER; PTHR13683; ASPARTYL PROTEASES; 1.
DR PANTHER; PTHR13683:SF817; OS07G0592200 PROTEIN; 1.
DR Pfam; PF14541; TAXi_C; 1.
DR Pfam; PF14543; TAXi_N; 1.
DR PRINTS; PR00792; PEPSIN.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
PE 3: Inferred from homology;
KW Aspartyl protease {ECO:0000256|ARBA:ARBA00022750,
KW ECO:0000256|RuleBase:RU000454}; Hydrolase {ECO:0000256|RuleBase:RU000454};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|RuleBase:RU000454};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..644
FT /note="Peptidase A1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004755641"
FT TRANSMEM 594..619
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 91..429
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT REGION 53..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 109
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 305
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
SQ SEQUENCE 644 AA; 71499 MW; AC2DE47EB51675F0 CRC64;
MALQRTQLIS VVSLILSLAQ WVVATGDSGE VLLLPNEGSR PAMILPLHHS VPDDSSVSDF
SPRRQLQRSQ SQRHPDARMR LYDDLLRNGY YTTRLWIGTP PQRFALIVDT GSTVTYVPCS
TCQHCGKHQD PKFQPEDSET YQPVKCTWQC NCDTDRKQCT YERRYAEMST SSGVLGEDVI
SFGNQSELSP QRATFGCEND ETGDLYTQHA DGIMGLGRGD LSIMDQLVEK KVISDAFSLC
YGGMGVGGGA MVLGGISPPA DMVFTHSDPG RSPYYNINLK EVHVAGKRLN LNPKVFDGKH
GTVLDSGTTY AYLPESAFLA FKDAIMKDTH SLKRISGPDP RYNDICFSGA GSDVSQLSKS
FPVVDMVFEN GHKLSLSPEN YLFRHLKVRG AYCLGVFSNG NDPTTLLGGI VVRNTLVMYD
REHTKIGFWK TNCSELWERL HVSDAPPPLS PKSEGTNLTK AFEPSVAPSP SPSQYNLPLG
ELQIAQIIVV ISFNISYMEM KPYITQLTGL IANELDVNTS QVHLLNVSSL GNGSLSKWLI
TPRPYADFFS NATAMSMIAR LSEHRMQLPD SLGSYKFLGW NAKPPLKRTW WQQYYLTVAL
AVLLTLLLGI SALGVFLIWR NRQQAEQSYE PVNVAVQEQE LQPL
//
