ID V7CQK5_PHAVU Unreviewed; 1201 AA.
AC V7CQK5;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=PHAVU_002G326400g {ECO:0000313|EMBL:ESW32487.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW32487.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; CM002289; ESW32487.1; -; Genomic_DNA.
DR RefSeq; XP_007160493.1; XM_007160431.1.
DR AlphaFoldDB; V7CQK5; -.
DR STRING; 3885.V7CQK5; -.
DR EnsemblPlants; ESW32487; ESW32487; PHAVU_002G326400g.
DR GeneID; 18639831; -.
DR Gramene; ESW32487; ESW32487; PHAVU_002G326400g.
DR KEGG; pvu:PHAVU_002G326400g; -.
DR eggNOG; KOG0920; Eukaryota.
DR OMA; LENIDEW; -.
DR OrthoDB; 53793at2759; -.
DR Proteomes; UP000000226; Chromosome 2.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF229; ATP-DEPENDENT RNA HELICASE DHX30; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00035; dsrm; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00358; DSRM; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 315..482
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 571..745
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1103..1168
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 112..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1181..1201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1185..1201
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1201 AA; 134948 MW; 689571A38DC10A03 CRC64;
MQKLCVCAVQ PLSLSAVTTT VPMAYSGIVQ GFIRFKTMTR LRCTPLRPSF PSISATPFHR
TAIRLRSSST TLQVVNVTRP RTTARKGTVA LPFLHQRSSS YGRFAYQDES SDDSDVEFAS
PPSHSQQVGD STLENIDEWR WKLTMLMRSK DEQEVVSREK KDRRDFEQLS TLATRMGLYS
RQYARVLVFS KAPLPNYRPD LDDKRPQREV VLPFGIHKEV DAHLHAHLSQ KATNSWSSLN
SLHKSSDPRS IPANEGMHEQ PEPMTHNSVV KQKILQKRSL QLLHRQQDWQ ESPEGQKMLE
FRRSLPAFKE KDAFLRVISE NQVVVVSGET GCGKTTQLPQ YILESETEAA RGAVCNIICT
QPRRISAMSV SERVAAERGE KLGESVGYKV RLEGMKGRDT RLLFCTTGVL LRRLLVDGNL
KGVTHVIVDE IHERGMNEDF LLIVLKELLP RRPDLRLILM SATLNAELFS SYFNGAPTMH
IPGFTFPVRA HFLEEILERT GHRLTPYNQI DDYGQEKTWK MQKQAQAFRK RKSQIASAVE
DALEVADFKR YSLRTQDSLS CWCPDSIGFN LIEHVLCHIV KNERPGAVLV FMTGWDDINS
LKDQLQAHPL LGDQSRVLIL ACHGSMASSE QRLIFENPEG GVRKIVLATN MAETSITIND
VVFVVDSGKA KETSYDALNN TPCLLPSWIS KAAARQRRGR AGRVQPGECY HLYPRCVYDA
FADYQMPELL RTPLQSLCLQ IKTLQLGSIS EFLSRALQPP EPLSVENAVE YLKIIGALDG
NENLTVLGQK LAMLPVEPKL GKMLILGTIF KCLDPIMTVV AGLSVRDPFV MPSDKKDLAE
SAKSQFAGRE YSDHLALVRA FEGWKDAETQ QAGYEYCWRN FLSSQTLKAI ESLRKQFLYL
LKDIGLVNNT PETYNAWSRE VHLIRAVICA GLFPGISSVV NKDKSIALKT MEDGQVLLYS
SSVNGCVPRI PYPWLVFNEK VKVNSVFLRD SSGISDSALL LFGGNVSRGG LDGHLKMLGG
YLEFFMKPEL AKTYLSLKTE LEELIQKKLL DPTQETQSHS QLLSAVRLLV SEDRCDGRFV
FGRQVPSQVK KETNAKSGVE GENFKNKLQT FLNRAGHESP TYKTKQLNNY QFRSTVIFNG
LNFAGQPCSS KKLAEKSAAA EALLWLKGDS HSSDAIDHAS VLLKKSNKKS RKKSFSGAKW
S
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