ID V7CVC3_PHAVU Unreviewed; 535 AA.
AC V7CVC3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Mur ligase central domain-containing protein {ECO:0000259|Pfam:PF08245};
GN ORFNames=PHAVU_001G060700g {ECO:0000313|EMBL:ESW33328.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW33328.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SIMILARITY: Belongs to the folylpolyglutamate synthase family.
CC {ECO:0000256|ARBA:ARBA00008276}.
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DR EMBL; CM002288; ESW33328.1; -; Genomic_DNA.
DR RefSeq; XP_007161334.1; XM_007161272.1.
DR AlphaFoldDB; V7CVC3; -.
DR EnsemblPlants; ESW33328; ESW33328; PHAVU_001G060700g.
DR GeneID; 18640530; -.
DR Gramene; ESW33328; ESW33328; PHAVU_001G060700g.
DR OMA; NLGWRIS; -.
DR OrthoDB; 7073at2759; -.
DR Proteomes; UP000000226; Chromosome 1.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.90.190.20; Mur ligase, C-terminal domain; 1.
DR Gene3D; 3.40.1190.10; Mur-like, catalytic domain; 1.
DR InterPro; IPR001645; Folylpolyglutamate_synth.
DR InterPro; IPR018109; Folylpolyglutamate_synth_CS.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR NCBIfam; TIGR01499; folC; 1.
DR PANTHER; PTHR11136:SF0; DIHYDROFOLATE SYNTHETASE-RELATED; 1.
DR PANTHER; PTHR11136; FOLYLPOLYGLUTAMATE SYNTHASE-RELATED; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF53623; MurD-like peptide ligases, catalytic domain; 1.
DR SUPFAM; SSF53244; MurD-like peptide ligases, peptide-binding domain; 1.
DR PROSITE; PS01011; FOLYLPOLYGLU_SYNT_1; 1.
DR PROSITE; PS01012; FOLYLPOLYGLU_SYNT_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226}.
FT DOMAIN 80..325
FT /note="Mur ligase central"
FT /evidence="ECO:0000259|Pfam:PF08245"
SQ SEQUENCE 535 AA; 57334 MW; 7935134E16CD13E2 CRC64;
MLLSLFRREF ARGVCSIRTL SSNPEMKDLS DYLDSLKNFE KSGLPRGAGT DSDEGFDLGR
MRRLMERFGN PHTNFKAVHI AGTKGKGSTA AFISNILRTE GYSVGCYTSP HILTIRERIL
LGRSGHPVSG KLLNDLFHRI KPKLEQAMKE ENGCISHFEV FTAMAFVLFA DENVDIAVIE
AGLGGARDAT NIISSSGLAA AVITTVGEEH LAALGGSLET IAMAKAGIIK QGCPLVLGGP
FVPHIERIIR DKAATMESPV VSAYDTGNRC TLKSFSIVNG RPYQICDIVI QVVKDLKMSC
KLHDVKLKML GDHQLQNAAT ATCVALCLRN LGWSISDESI RSGLEHTHLL GRSQFLTSEE
AGVLGLTGAT VLLDGAHTKE SAKALMKTVK MTFPKAPLIF VVAMASDKDH VGFAREILLG
GHVETVLLTE AAIAGGVTRT TSASLLRDSW IKASDELGIG IFHDGMAEYN ELIDQPVGSE
SNLGDGMTIL ATESSLKSSL RTANKILTRR GEEKGVIVFT GSLHIAASVL ASLSG
//
