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Database: UniProt
Entry: V7ENS7_9RHOB
LinkDB: V7ENS7_9RHOB
Original site: V7ENS7_9RHOB 
ID   V7ENS7_9RHOB            Unreviewed;       458 AA.
AC   V7ENS7;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   25-OCT-2017, entry version 31.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=Q27BPR15_04220 {ECO:0000313|EMBL:ESW61832.1};
OS   Rhodobacter sp. CACIA14H1.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=1408890 {ECO:0000313|EMBL:ESW61832.1, ECO:0000313|Proteomes:UP000018503};
RN   [1] {ECO:0000313|EMBL:ESW61832.1, ECO:0000313|Proteomes:UP000018503}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24435858;
RA   Lima A.R., Siqueira A.S., Dos Santos B.G., da Silva F.D., Inada D.T.,
RA   Lima C.P., Cardoso J.F., Vianez-Junior J.L., Nunes M.R.,
RA   Goncalves E.C.;
RT   "Draft Genome Sequence of Rhodobacter sp. Strain CACIA 14H1, a
RT   Heterotrophic Bacterium Obtained from a Nonaxenic Culture of a
RT   Cyanobium Species.";
RL   Genome Announc. 2:e01116-13(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ESW61832.1}.
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DR   EMBL; AYNO01000018; ESW61832.1; -; Genomic_DNA.
DR   PATRIC; fig|449393.3.peg.861; -.
DR   Proteomes; UP000018503; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018503};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018503}.
FT   DOMAIN      150    280       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      366    435       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     158    165       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   458 AA;  52137 MW;  0EB8AC0DE7A80FA1 CRC64;
     MLNETWGLVR EELIKRVGRN NYVTWIEPLK FSDLRNGVAR FEVPTSFFGD WVSRNFSDHI
     RAQLNTAGQQ VERIEFAVAN RPAAPVQRPA TPAKPAAQPR LRSNGRTGDA DEMPGAPLDS
     RFTFDSFVVG KPNELAHAAA RRVAEGGPVT FNPLFLYGGV GLGKTHLMHA IAHELQTRQP
     HLRVLYLSAE QFMYRFVQAL RERQIMDFKE IFRSVDVLMV DDVQFIAGKD STQEEFFHTF
     NALVDQNKQI VISADRAPGE IKDLEERIKS RLQCGLVVDL HPTDYELRLG ILQQKVELYR
     TQYSSLAITD GVLEFLAHRI TTNVRVLEGA LTRLFAFASL VGREITLELA QDCLADILRA
     SDRKLTIEEI QRKVAEHYNI RLSDMIGPKR VRTIARPRQI AMYLAKQLTP RSLPEIGRRF
     GGRDHTTIMH GVRKIEELMA TDSQLNDDLQ MLRRLLQG
//
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