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Database: UniProt
Entry: V7I507_9CLOT
LinkDB: V7I507_9CLOT
Original site: V7I507_9CLOT 
ID   V7I507_9CLOT            Unreviewed;       449 AA.
AC   V7I507;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   25-OCT-2017, entry version 30.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=T472_0207410 {ECO:0000313|EMBL:ETA81325.1};
OS   Youngiibacter fragilis 232.1.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Youngiibacter.
OX   NCBI_TaxID=994573 {ECO:0000313|EMBL:ETA81325.1, ECO:0000313|Proteomes:UP000017747};
RN   [1] {ECO:0000313|EMBL:ETA81325.1, ECO:0000313|Proteomes:UP000017747}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=232.1 {ECO:0000313|EMBL:ETA81325.1,
RC   ECO:0000313|Proteomes:UP000017747};
RX   PubMed=24459265;
RA   Wawrik C.B., Callaghan A.V., Stamps B.W., Wawrik B.;
RT   "Genome Sequence of Youngiibacter fragilis, the Type Strain of the
RT   Genus Youngiibacter.";
RL   Genome Announc. 2:e01183-13(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ETA81325.1}.
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DR   EMBL; AXUN02000135; ETA81325.1; -; Genomic_DNA.
DR   RefSeq; WP_023389152.1; NZ_AXUN02000135.1.
DR   EnsemblBacteria; ETA81325; ETA81325; T472_0207410.
DR   PATRIC; fig|994573.3.peg.1376; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000017747; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000017747};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017747}.
FT   DOMAIN      143    272       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      356    425       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     151    158       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   449 AA;  50533 MW;  E8191265AFFC23E8 CRC64;
     MDARLKENWD NILKVLKVEI MSEVSYNTWI AGLVPIGTRG GVFYIDVPNE LTLDILRQRY
     KVLIKEAVKH VLDEDIEVDY VIGGLPDVAP VVETKTAAPV PEVPRSNNGT LNTKYTFDSF
     VIGNSNRFAH AASVAVAESP ANAYNPLFLY GGVGLGKTHL MHAIGHHILT QNPKANVVYV
     SSEKFTNELI NSIRYDKNAD FRNKYRNVDV LLVDDIQFIA GKESTQEEFF HTFNELYEAR
     KQIIISSDRP PNEIPTLEDR LRTRFAWGLQ ADIQAPDFET RIAILKKKAE TENYVVSSEV
     MVYIATKIKS NIRELEGALI RVMAYSSLTN NKNITVDLAA EALKDIISST QSKSITIDLI
     QDVVSNYYNM SIQELKSQRR TRNVAFPRQI AMYLSRKLTD MSLPKIGEEF GGRDHTTVIH
     AYEKISEALK TDDALAGAIK LITKKLTSQ
//
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