ID   V8BD97_STRPA            Unreviewed;       380 AA.
AC   V8BD97;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=Cobalamin-independent methionine synthase MetE C-terminal/archaeal domain-containing protein {ECO:0000259|Pfam:PF01717};
GN   ORFNames=HMPREF1195_00900 {ECO:0000313|EMBL:ETD12767.1};
OS   Streptococcus parasanguinis CC87K.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1073372 {ECO:0000313|EMBL:ETD12767.1, ECO:0000313|Proteomes:UP000018716};
RN   [1] {ECO:0000313|EMBL:ETD12767.1, ECO:0000313|Proteomes:UP000018716}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC87K {ECO:0000313|EMBL:ETD12767.1,
RC   ECO:0000313|Proteomes:UP000018716};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Allen-Vercoe E., Daigneault M., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA   Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Streptococcus parasanguinis CC87K.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETD12767.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AZJD01000004; ETD12767.1; -; Genomic_DNA.
DR   RefSeq; WP_014713636.1; NZ_KI669401.1.
DR   AlphaFoldDB; V8BD97; -.
DR   PATRIC; fig|1073372.3.peg.920; -.
DR   HOGENOM; CLU_058877_0_0_9; -.
DR   OrthoDB; 6430685at2; -.
DR   Proteomes; UP000018716; Unassembled WGS sequence.
DR   GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR   CDD; cd03311; CIMS_C_terminal_like; 1.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR002629; Met_Synth_C/arc.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR   PANTHER; PTHR43844:SF1; METHIONINE SYNTHASE; 1.
DR   Pfam; PF01717; Meth_synt_2; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
FT   DOMAIN          172..353
FT                   /note="Cobalamin-independent methionine synthase MetE C-
FT                   terminal/archaeal"
FT                   /evidence="ECO:0000259|Pfam:PF01717"
SQ   SEQUENCE   380 AA;  42309 MW;  40B0ED58E85F11AB CRC64;
     MTHTHAPYRV DHVGSFLRPA ALVQAREDFA AGKISQADLT KVEDQAIRDL VEKEIAAGLK
     SVTDGEFRRA YWHLDFFWGF GGIDHVQAAQ GYQFHDETTK ADSALVVGKI TGANHPFVEH
     YKFLRDLVAD VDGVEAKYTI PAPAQFYFEL IRDAEHVEQL NTIYPDFAAV REDIKQAYLQ
     VIQDLYDAGL RTLQVDDCTW GVLVDDNFLT AWGAAQGKSK DEVRRELADL FLTFNNDVYQ
     HVPAGLTVNT HVCRGNFHST WASSGGYAPI AKELLGEEAV NAYFLEFDTD RAGGFEPLAE
     VTPGKGVVLG LLTSKSGQLE NKDEVIARIK EASQYVPLEN LYLSTQCGFA STEEGNILTE
     EDQWKKIGLI KEIVAEVWGE
//