ID V8CG66_9HELI Unreviewed; 374 AA.
AC V8CG66;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=2-oxoglutarate synthase subunit alpha {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF2087_01813 {ECO:0000313|EMBL:ETD25975.1};
OS Helicobacter canis NCTC 12740.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1357399 {ECO:0000313|EMBL:ETD25975.1, ECO:0000313|Proteomes:UP000018688};
RN [1] {ECO:0000313|EMBL:ETD25975.1, ECO:0000313|Proteomes:UP000018688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 12740 {ECO:0000313|EMBL:ETD25975.1,
RC ECO:0000313|Proteomes:UP000018688};
RG The Broad Institute Genomics Platform;
RA Earl A., Fox J.G., Shen Z., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Abouelleil A., Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Helicobacter canis NCTC 12740.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETD25975.1}.
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DR EMBL; AZJJ01000007; ETD25975.1; -; Genomic_DNA.
DR RefSeq; WP_023930872.1; NZ_KI669458.1.
DR AlphaFoldDB; V8CG66; -.
DR STRING; 1357399.HMPREF2087_01813; -.
DR PATRIC; fig|1357399.3.peg.1902; -.
DR eggNOG; COG0674; Bacteria.
DR HOGENOM; CLU_017038_0_1_7; -.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000018688; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154:SF14; 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018688}.
FT DOMAIN 14..243
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 275..367
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 374 AA; 41264 MW; 7082760C47929D77 CRC64;
MREVISGGNE LVAKAAIDAG CRFYGGYPIT PSSDIMHEMS VLLPKHNGHF IQMEDEISGI
CAALGAAMSG VKSMTGSSGP GISLKVEQIG LGFMAEVPLV IADVMRSGPS TGMPTRVAQG
DVGFLKHPTH GDFKSVAIAP GNLEESYTQT IRAFNLAEEL MTPVFLLMDE TIGHMYGKTY
IPDIEEVQKS VINRRTFTGD PKSYQPYDVK PDEGAILNPF FQGYRYHITG LHHGPLGFPT
EDAKMGQALI DRLFNKIESK ESYICQNEEL DLEGAEIAII AYGSTALSVK EAMIELKKMG
KKVGLFRPIT LWPSPKTRLK QLGETYKKIL VIELNKGQYL EEIERVLERK VEFMGQANGR
SISPTQIIDR IKEM
//
