ID V8N5E7_OPHHA Unreviewed; 249 AA.
AC V8N5E7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE RecName: Full=PLA2c domain-containing protein {ECO:0000259|PROSITE:PS51210};
DE Flags: Fragment;
GN ORFNames=L345_16795 {ECO:0000313|EMBL:ETE57489.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE57489.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE57489.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE57489.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE57489.1}.
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DR EMBL; AZIM01008351; ETE57489.1; -; Genomic_DNA.
DR AlphaFoldDB; V8N5E7; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0004620; F:phospholipase activity; IEA:InterPro.
DR GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002642; LysoPLipase_cat_dom.
DR PANTHER; PTHR10728; CYTOSOLIC PHOSPHOLIPASE A2; 1.
DR PANTHER; PTHR10728:SF35; PHOSPHOLIPASE A2; 1.
DR Pfam; PF01735; PLA2_B; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51210; PLA2C; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00555};
KW Lipid degradation {ECO:0000256|PROSITE-ProRule:PRU00555};
KW Lipid metabolism {ECO:0000256|PROSITE-ProRule:PRU00555};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 17..249
FT /note="PLA2c"
FT /evidence="ECO:0000259|PROSITE:PS51210"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE57489.1"
SQ SEQUENCE 249 AA; 29031 MW; 7C566626A6525050 CRC64;
MGHLVKNESF DLHVKTKEWP KELDERLGYD LCAEEQDFLR KRRKYVAAAI KKTLQLQKEL
KDDEVPVIAV MTTGGGTRSF TAMYGSILGL QKLNLLDCLT YLTGLSGTTW TMCKLYEDPD
WSQKYLEEAI NKARRQVTKS KFNCFSSDKL KYYYDELNQK IKEGHSTSFI DLWGLIIESM
FHDEKDNHTL SDQRMAVNEG QNPFPIYLAV SLKENYSAQD FKEDFGNEFF MGRLMKKFPE
IRICFMQGK
//
