ID V8NBQ5_OPHHA Unreviewed; 306 AA.
AC V8NBQ5;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 22-FEB-2023, entry version 16.
DE SubName: Full=5-oxoprolinase {ECO:0000313|EMBL:ETE59505.1};
DE Flags: Fragment;
GN Name=Oplah {ECO:0000313|EMBL:ETE59505.1};
GN ORFNames=L345_14760 {ECO:0000313|EMBL:ETE59505.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE59505.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE59505.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE59505.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE59505.1}.
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DR EMBL; AZIM01005535; ETE59505.1; -; Genomic_DNA.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 1..136
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 156..288
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT NON_TER 306
FT /evidence="ECO:0000313|EMBL:ETE59505.1"
SQ SEQUENCE 306 AA; 33329 MW; 92B5766257B0C54C CRC64;
MGTTVATNAL LERKGERFAL LITRGFRDLL YIGNQARPSI FDLEVRMPEV LYEAVLEVDE
RLVLHRDGCP LSDSEQRVTG LTGEAVVVKQ PVNLLALRVE LEALLAQGIH SLAVVLLHSY
LWPGHEQQVG ALARELGFRQ VSLSSEVMPM VRMVPRGYTA CIDAYLTPCI LRYLQSFRDG
FASQLQGVPV AFMRSDGGLT PMEAFSGSRA VLSGPAGGVV GYAVTSYHRA EERPVIGFDM
GGTSTDVSRY AGEYEHVFEA TTAGISIQVP QLDINTVAAG GGSRLFFRGX PELRAICPPS
SFERGR
//
