ID V8NKT0_OPHHA Unreviewed; 462 AA.
AC V8NKT0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=RNA-binding protein 47 {ECO:0000313|EMBL:ETE62665.1};
DE Flags: Fragment;
GN Name=RBM47 {ECO:0000313|EMBL:ETE62665.1};
GN ORFNames=L345_11577 {ECO:0000313|EMBL:ETE62665.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE62665.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE62665.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE62665.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE62665.1}.
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DR EMBL; AZIM01003122; ETE62665.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NKT0; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 2.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF6; RNA-BINDING PROTEIN 47; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 71..144
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 151..247
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 260..332
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE62665.1"
FT NON_TER 462
FT /evidence="ECO:0000313|EMBL:ETE62665.1"
SQ SEQUENCE 462 AA; 51619 MW; CB4CAF9CA50A0C52 CRC64;
MTAEDSTARM NNDSSNMQTN KIPEGLSGAP NEAALLQLLD RTGYTMIQEN GQRKYGGPPP
GWEGLHPPRG CEVFVGKIPR DVYEDELVPV FETTGRIYEM RLMMDFDGKN RGYAFVMYTQ
KYEAKRAVKE LNNYEIRPGR LLGVCCSVDN CRLFIGGIPK TKKREEILEE ISKVTEGVLD
VIVYASAADK MKNRGFAFVD AADKMKNRGF AFVEYESHRA AAMARRKLMP GRIQLWGHQI
AVDWAEPEID VDEDVMETVK ILYVRNLMIE TTEETIKKVF GQFNPSSIER VKKIRDYAFV
HFTSREDAVH AMNNLNGTEL EGSCLEVTLA KPVDKEQYTR YQKAAKGGAG AGATAADVTQ
QPNYVYSCDP YTLTYYGYPY NALIGPNREY FVKAGNIRGR GRGAAGNRAP GPRGSYLGGY
SAGRGIYSRY HEGKGKQQEK GYEMVPNLEL PAVSPMAIKP GT
//
