ID V8NPG6_OPHHA Unreviewed; 419 AA.
AC V8NPG6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Dynein heavy chain 3, axonemal {ECO:0000313|EMBL:ETE64179.1};
DE Flags: Fragment;
GN Name=Dnah3 {ECO:0000313|EMBL:ETE64179.1};
GN ORFNames=L345_10060 {ECO:0000313|EMBL:ETE64179.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE64179.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE64179.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE64179.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE64179.1}.
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DR EMBL; AZIM01002364; ETE64179.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NPG6; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR PANTHER; PTHR46961:SF8; DYNEIN AXONEMAL HEAVY CHAIN 3; 1.
DR PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF18199; Dynein_C; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 1..83
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 115..415
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE64179.1"
SQ SEQUENCE 419 AA; 47984 MW; BA820AA1191F0CF4 CRC64;
MLFGLCFFHA LVQERRNFGP LGWNIPYEFN ESDLRISLRQ IQMFLNEYEE TPFEALTYLT
GECNYGGRVT DDKDRRLLLS LLSLSYIDYL RTLPISTHPE IFGLHENADI TKDNQETNLL
FDGVLLTLPR EAGGGGKSPQ ETVEELAQDV LSKLPNDFDL ERVMKLYPVL YEESMNTVLR
QELIRFNRLT EVVRSSLISL GKAIKGLVLM SSELEEVFNS MIVGKVPAMW AAKSYPSLKP
LGSYVTDLVT RLVFFQEWIK HGPPNVFWIS GFYFTQSFLT GVSQNYARKY TIPIDHIGFE
FEVMGKEHTM EQMPEDGAYV KGLFLEGARW DRVGMQIGES FPKILYDTLP IIWLKPGESS
KFLHERIYLC PVYKTSARRG ILSTTGHSTN YVLSIELPSD LPQKHWINRG VAALCQLDD
//
