ID V8NVK0_OPHHA Unreviewed; 371 AA.
AC V8NVK0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Amidophosphoribosyltransferase {ECO:0000256|ARBA:ARBA00033770};
DE AltName: Full=Glutamine phosphoribosylpyrophosphate amidotransferase {ECO:0000256|ARBA:ARBA00033776};
DE Flags: Fragment;
GN Name=PPAT {ECO:0000313|EMBL:ETE65718.1};
GN ORFNames=L345_08508 {ECO:0000313|EMBL:ETE65718.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE65718.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE65718.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE65718.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE65718.1}.
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DR EMBL; AZIM01001803; ETE65718.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NVK0; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR InterPro; IPR017932; GATase_2_dom.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR PANTHER; PTHR11907; AMIDOPHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR11907:SF0; AMIDOPHOSPHORIBOSYLTRANSFERASE; 1.
DR Pfam; PF13522; GATase_6; 1.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR PROSITE; PS51278; GATASE_TYPE_2; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:ETE65718.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Transferase {ECO:0000313|EMBL:ETE65718.1}.
FT DOMAIN 1..176
FT /note="Glutamine amidotransferase type-2"
FT /evidence="ECO:0000259|PROSITE:PS51278"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE65718.1"
SQ SEQUENCE 371 AA; 41323 MW; 47AD59432C1A0D7D CRC64;
MGLVNHVFSE DSLKKLYVSN LGIGHTRYST SGVSVLDNCQ PFVVETLHGK IAVAHNGELT
NAMRLRRKLM RHGVGLSTSS DSELITQLLA FTPPLEQDDT PDWVARYYRE VMPGEIVKIS
RYDVQTLDIV PRPQGDPAAF CIFEYVYFAR PDSIFEGQMV YSVRRRCGQQ LAIEAPVEAD
LVSTVPESAT PAALGYAQKC GLPYIEVLCK NRYVGRTFIQ PNMRLRQLGV AKKFGVLSDN
FRGKRVVLID DSIVRGNTIS PIIKLLRESG AKEVHIRVAS PPIKFPCYMG INIPTKEELI
ANRPEFKDLA GYIGADSVVY LSVDGLVSSV QESIKARQDH ENNLKTNKFK SGKIGHCTAC
LVGKYPVELE W
//
