ID V8NVP5_OPHHA Unreviewed; 254 AA.
AC V8NVP5;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Cysteine and histidine-rich domain-containing protein 1 {ECO:0000256|ARBA:ARBA00034547};
DE AltName: Full=CHORD domain-containing protein 1 {ECO:0000256|ARBA:ARBA00034558};
DE Flags: Fragment;
GN Name=CHORDC1 {ECO:0000313|EMBL:ETE66016.1};
GN ORFNames=L345_08208 {ECO:0000313|EMBL:ETE66016.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE66016.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE66016.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE66016.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE66016.1}.
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DR EMBL; AZIM01001687; ETE66016.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NVP5; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd06488; p23_melusin_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 4.10.1130.20; -; 1.
DR InterPro; IPR007051; CHORD_dom.
DR InterPro; IPR039790; CHRD1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR PANTHER; PTHR12621:SF7; CHORD DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR12621; CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN; 1.
DR Pfam; PF04968; CHORD; 1.
DR Pfam; PF04969; CS; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51401; CHORD; 1.
DR PROSITE; PS51203; CS; 1.
PE 4: Predicted;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 84..143
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 154..236
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE66016.1"
SQ SEQUENCE 254 AA; 28890 MW; 7D7861A20DD6CAC6 CRC64;
MYDKFQQGCT KGFHNSEKPP EPVKPEVKTT SERKELADLK PKFQEHIIQA PKPVEAIQRP
RNVLKESSYF TEDDSDEIKI GTPCKNAGCS KTFEGPGSTE DACIYHAGVP IFHEGMKYWS
CCKRKTSDFN TFLAQEGCTT GTHLWIKKDA GKKVVPCRHD WHQTGREVII SIYAKNSIPE
LSRLNIHIVF EGDKVFNQNL NLWGVIDVKR SYVNMTATKI ELTMRKAEPM LWAGLELPAS
KLQHKEPQNI VEQA
//
