GenomeNet

Database: UniProt
Entry: V8P551_OPHHA
LinkDB: V8P551_OPHHA
Original site: V8P551_OPHHA 
ID   V8P551_OPHHA            Unreviewed;       534 AA.
AC   V8P551;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   25-OCT-2017, entry version 22.
DE   SubName: Full=Cyclic nucleotide-gated olfactory channel {ECO:0000313|EMBL:ETE69699.1};
DE   Flags: Fragment;
GN   Name=CNGA2 {ECO:0000313|EMBL:ETE69699.1};
GN   ORFNames=L345_04505 {ECO:0000313|EMBL:ETE69699.1};
OS   Ophiophagus hannah (King cobra) (Naja hannah).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata;
OC   Toxicofera; Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX   NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE69699.1, ECO:0000313|Proteomes:UP000018936};
RN   [1] {ECO:0000313|EMBL:ETE69699.1, ECO:0000313|Proteomes:UP000018936}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Blood {ECO:0000313|EMBL:ETE69699.1};
RX   PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA   Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA   McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA   Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA   de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA   Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA   Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W.,
RA   Dirks R.P., Spaink H.P., Duboule D., McGlinn E., Kini R.M.,
RA   Richardson M.K.;
RT   "The king cobra genome reveals dynamic gene evolution and adaptation
RT   in the snake venom system.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ETE69699.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AZIM01000711; ETE69699.1; -; Genomic_DNA.
DR   Proteomes; UP000018936; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR032406; CLZ_dom.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF16526; CLZ; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS00889; CNMP_BINDING_2; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018936};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM     12     32       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    140    164       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    218    240       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      322    428       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   COILED      463    515       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:ETE69699.1}.
SQ   SEQUENCE   534 AA;  61813 MW;  03827580A96E7CB1 CRC64;
     MDPAGKWYYR WLLVIAVPVL YNWCVLVARA CFNELQRRYL LCWLVLDYLA DGIYIMDIVF
     RMNTGEREEG LLVKDFKKLR AKYIATLQFK LDILSILPTD LAYFVVGIHR PELRFNRLLH
     FPRMFECFDR TETRTSYPNI FRICNLVMYI LVIIHWNACI YYAISKAIGF GEDTWVYPNI
     SDPEYGYLTR EYVYCLYWST LTLTTIGETP PPVRDEEYLF VIFDFLIGVL IFATIVGNVG
     SMISNMNATR AEFQAKIDAV KHYMHFRKVS KEMEAKVIRW FDYLWTNKKT VDEWEVLKNL
     PDKLRAEIAI NVHLETLKKV RIFQDCEAGL LVELVLKLRP QVFSPGDYIC RKGDIGKEMY
     IIKEGKLAVV ADDGITQYAL LTAGCCFGEI SILNIKGSKM GNRRTANIRS IGYSDLFCLS
     KEDLMEAVTE YPGAKRVLEE RGREILTKEG LLDEAAAAES MEAMDVGQKL DRLETSLETL
     NARFSRLLAE YDAAQMKLKQ RLTSLEAKVK EEKREELFPE GFISPLGEEE KAKP
//
DBGET integrated database retrieval system