ID V8P647_OPHHA Unreviewed; 717 AA.
AC V8P647;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ankyrin repeat and BTB/POZ domain-containing protein 2 {ECO:0000313|EMBL:ETE70014.1};
DE Flags: Fragment;
GN Name=Abtb2 {ECO:0000313|EMBL:ETE70014.1};
GN ORFNames=L345_04177 {ECO:0000313|EMBL:ETE70014.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE70014.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE70014.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE70014.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE70014.1}.
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DR EMBL; AZIM01000637; ETE70014.1; -; Genomic_DNA.
DR AlphaFoldDB; V8P647; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR CDD; cd18526; BACK_ABTB2; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46071; ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR46071:SF3; ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT REPEAT 251..283
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 297..329
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 482..639
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE70014.1"
SQ SEQUENCE 717 AA; 80593 MW; 7002D142F44F9C22 CRC64;
MVQLEAVSSK LWANYEEQIC RAHIGVLSLP AYFSPYNDGS ICSNGRADAY AQLELRTLEQ
SLLATCVGSI SELSDLVSRA MHHMQCLTTL RPGMSPVRQT RQQQPPITWS PDALHTLYYF
LRCPQMESME NPNLDPPRMA LSNERPFMLL PPLMEWMRVA ITYAEHRRSL TVDSDDIRQT
ARLLLPGLDC EPRQLKPECC FSSFRRMDAK AATKKFQQDL GFRMLNCGRT DLINQAIEAL
GPEGVNTMDD QGMTPLMYAC SAGDEAMVQM LIDAGANLDI PVPGSSSRYP SVHPDSRHWT
ALTFAVLHGH ISVVQLLLDA GAHVEGSAVN SNYELVSLLL SRGADPLLSM LEANGISSSL
HEDMNCFSHA AAHGHRNVLR KLLTQPQQSK GDVLSLEEIL AEGVENDTSS QGSSNEGQVK
LCKTRMKALQ EAMYYSAEHG YVDITMELRV LGIPWKLHVW IESLRTTFYQ SRYSVVQNLL
REFVTIKEEE YNEELVTDGL KLMFEILRTS KNDSISQHLA AIFTHCYGSS PIPNIPEIRK
TLPARLASSR KADDPENSKN EFKTLMTNKT GQDSQGNKIV EISDMRYNIF KMLMQYLYYG
GTEAMEIPIA DILELLSAAS LFQLDGLQRH CEILCAQTIN TESCVHIYKY AKIHNAPELA
SFCEGFFLKH MNSLVQQESF RQLIYGRNSR VQGLDPLQDL QSTLASRLHS VYVTSRV
//
