ID V8PA85_OPHHA Unreviewed; 1641 AA.
AC V8PA85;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=InaD-like protein {ECO:0000313|EMBL:ETE70812.1};
DE Flags: Fragment;
GN Name=INADL {ECO:0000313|EMBL:ETE70812.1};
GN ORFNames=L345_03373 {ECO:0000313|EMBL:ETE70812.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE70812.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE70812.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE70812.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE70812.1}.
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DR EMBL; AZIM01000478; ETE70812.1; -; Genomic_DNA.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 10.
DR Gene3D; 2.30.42.10; -; 11.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR InterPro; IPR015132; L27_2.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR PANTHER; PTHR19964:SF44; PATJ HOMOLOG; 1.
DR Pfam; PF09045; L27_2; 1.
DR Pfam; PF00595; PDZ; 10.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 11.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 11.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 11.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 5..65
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 77..174
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 201..281
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 316..404
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 431..517
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 571..645
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 867..984
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1067..1118
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1189..1278
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1291..1373
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1436..1522
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1558..1641
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 536..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 995..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 995..1015
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE70812.1"
SQ SEQUENCE 1641 AA; 180459 MW; 4F52CEE351A177CE CRC64;
MFWGNPTDKQ QILKILERLL MKLHEKGDTS HSDNLAFLYN TLKNPLFNHV LTLQQSIKQL
KEQVSNKRER FDGEIEYIDI EKPSNRGLGF SVIALKNQSF GEVGIFVKEV QPGSIAASFL
TVTYAYPRDQ RLKENDQILA VNHTPLDLNI SHQQAILLLQ QSTGSLHLVV AREPTQNSSR
ISSAVSDDNV PEMVNWGHTE EVELINDGSG LGFGIVGRKT SGVVVRTIVP DGLADRDGRL
RTDDHILEIG GINVQGMSSE QVAQVLRNCG NHVKMVVARS PLSEISTTPP TPVAGPVGEL
ATIQDRESDT ENEIHEVKLT KKDGQSLGIT IVGYSGVSDS GEASGIFIKN VIPDSAADHN
GQIKVNDKII AVNRINIQNY TNQEVVEALR KTGPVVHLTL LRKKPYYAET ELDRGKVPPS
VVTIDTPIAD DAELQKYSKL LPIHTLRLGV ELDTFEGHHY ISSIATDGPI AKLGLLQLED
ELLEVNGVQL YGKSRREAVS FLKEVPPPFT LICCRRLFDD DTESFVDEPT ATITHSLEPK
VKFENPEEQQ EDEEQEDEDV ELALWSSEVR DIVLVKDAKI GLGFSILDYQ DPLDPTKTAF
VISSLVPCGV AERGGALFPG DRLVSVNDMY LHNIGLEEAV EVLKSVPPGE VHLGVCKPLV
SETDVDQESW EMHEILKPME EYLGEEREML VDEVYDMDQD YGRGPSINMR EISSSPVVDI
ATEGHWVEEL DSTKMVELNP ANNLNTEENE EKSTNNSLFH GVSVEYSQEN PMLDGIANHS
DPKEDLCTDV DHEKYNMKNE DIDPSSSQDS ALCRIVLSSE LPEREEGEGE ETPIFSHWGT
PQMYADKYFN IYFALIIIWG SILSPYRIEI FREPHVPLGI SIVGGHTVIK RLKNGEELKG
IFIKQVLEDS PAGRTKALKT GDKILEVFQL TDLFPGFGTE EVNLNELISV QVSGTDLQNA
THEEAVEAIK NAGNPIVFVV QSLSTLPRVI SVINPKKKKD DEDQDTEETE KKKSGIPPPM
KLPPPYKAAR KSSSDDPEEK EDEEEENVFT EEKIRQRYAE LPGELHIIEL EKDKNGLGLS
LAGNKDRSHM SIFVVGISPD GPAGKDGRMH IGDELLEVIN EDAFNQMAVA PFPLPSCTQS
SNEDISSKAE KQVIEDQQVK ADQAPENLRN QLKQTKFSTV NPIPINLHEI SLAPESSYSP
ETEFSNQSMN LLFPSEEDAI VIHEVYEEGA AARDGRLWAG DQILEVNGID LRNASHEDAI
TALRQTPPKV QLVVYRDEAH YKDEENLEIF LVDLQRKMGR GLGLSIVGKR NGSGVFISDI
VKGGAADLDG RLIQGDQILS VNGEDVRHAS QEVVATILKC AQGLVQLEIG RLRAGSSLSS
RKTSQNSQMS QHNVHSHFHP TFAPVISTLQ NLVSTKRSSA DPSQRNSVGA DISPRTVEIT
RGLNDALGIS IAGGKGSPLA DIPIFIAMIQ ANGVAARTHK LRVGDRIVSI NGQPLDGLSH
AEVVNLLKNA YGTIILQVVA DTNISAIASQ IENMTSSTNF TPPTEHHSEY PEAPQPKIIV
LEKGSDGLGF SIVGGFGSPQ GDLPIYVKTI FAKGAAADDG RLKRGDQILA VNGQSLEGVT
HEQAVAILKH QKGEVTLTVL P
//
